CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12816
Family Name Sodium-dependent noradrenaline transporter and Sodium-dependent serotonin transporter inhibitor 2-[5-chloro-3-methyl-2-[(R)-phenyl-[(3S)-pyrrolidin-3-yl]methoxy]phenyl]pyridine family
No. of Seeds 2 No. of Other Members 7
Family Centroid CFAMM00371106 Functional Category Bioactive
Superfamily Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha Binder Superfamily 2
Class Class 3170

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand monosubstituted indole derivat... 14 475
Amyloid beta A4 protein Inhibitor Florbetapir F-18 Family 8 265
Nicotinic acetylcholine receptor Ligand AZD0328 Family 11 97
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 9 115
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 13 22
Alpha-1A adrenergic receptor Ligand RS-17053 Family 9 6
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 4 35
RAC-gamma serine/threonine-protein kinase Inhibitor A-443654 F... 67 59
5-hydroxytryptamine receptor 2A and Amine oxidase [flavin-cont... 4 32
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 3 24
D(2) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 2 10
Glucagon receptor and Mitogen-activated protein kinase 14 liga... 6 5
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 11 4
Sodium-dependent serotonin transporter inhibitor SureCN6575591... 2 0
Prostaglandin D2 receptor 2 ligand 2-[4-chloro-2-[2-(4-propylp... 2 13
Sodium-dependent serotonin transporter and D(2) dopamine recep... 3 0
RAC-alpha serine/threonine-protein kinase and cAMP-dependent p... 3 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 2 0
Glucocorticoid receptor and Mineralocorticoid receptor ligand ... 1 2
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 4
Sodium-dependent serotonin transporter and Sodium-dependent no... 3 8
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 0
Glucagon receptor ligand SureCN2647807 family 3 7
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-04UHB... 4 2
Sodium-dependent noradrenaline transporter and Sodium-dependen... 1 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45931 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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