CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12819
Family Name Cannabinoid receptor 2 ligand 1-adamantyl(1,3-dihydroisoindol-2-yl)methanone family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00104760 Functional Category Bioactive
Superfamily Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 1-(2-adamantyl)-3-benzylpyrrolidin-2-one Superfamily
Class Class 620

Cousin Family NamesSeedsMembers
Opioid receptor Ligand Methadone Family 3 39
Glutathione S-transferase Inhibitor Praziquantel Family 5 167
DNA Binder Procarbazine Family 8 358
Noradrenergic re-uptake Inhibitor Milnacipran Family 7 51
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 2 9
Peripheral carotid chemoreceptor Ligand Doxapram Family 4 36
Microsomal triglyceride transfer protein large subunit Inhibit... 15 208
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 2 18
Bavisant family 9 65
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-m... 8 37
Beta-secretase 1 Inhibitor N-(1-benzylpiperidin-4-yl)-4-sulfan... 7 62
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 5-(4-chloro-... 10 52
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 41 24
Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 1-(2-... 1 1
Cannabinoid receptor 1 Ligand N-(3,3-diphenyl)propyl-2-phenyla... 4 18
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 9 66
Sodium channel protein type 1 subunit alpha and Sodium channel... 4 31
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 2 80
Melatonin receptor type 1A Ligand N-(2,3-dihydro-1h-phenalen-2... 8 13
5-hydroxytryptamine receptor 2A Ligand N-(1-(3-bromobenzyl)pip... 6 10
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Voltage-dependent calcium channel gamma-1 subunit Ligand NP-11... 8 9
Vasopressin V1a receptor and Vasopressin V2 receptor ligand [2... 2 4
Kappa-type opioid receptor ligand 1-[(2S)-2-(pyrrolidin-1-ylme... 4 0
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 1 18
P2X purinoceptor 7 inhibitor N-(1-adamantylmethyl)-2,5-dichlor... 3 4
Acetylcholinesterase inhibitor 5-benzoyl-2-[2-(1-benzylpiperid... 2 3
Neuromedin-K receptor ligand SureCN2477089 family 2 4
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 3 0
Histamine H3 receptor and Potassium voltage-gated channel subf... 9 0
Substance-P receptor ligand (3R,4R)-1-(1-acetylpiperidine-4-ca... 9 1
Cathepsin K and Cathepsin S inhibitor (1R,2R)-N-(cyanomethyl)-... 1 0
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 3 1
C-C chemokine receptor type 5 ligand 1-[[(3S,4S)-1-(cyclohexyl... 1 0
P2X purinoceptor 7 inhibitor N-(1-adamantylmethyl)-2-bromobenz... 1 1
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 4 1
Histamine H3 receptor ligand [(3aR,6aR)-4-[4-[2-[(2R)-2-methyl... 6 0
Beta-secretase 1 inhibitor [(3'S,4R)-7-bromospiro[2,3-dihydro-... 1 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor [4-(2... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26851 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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