CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1282
Family Name Translocator protein inhibitor SureCN13502542 family
No. of Seeds 20 No. of Other Members 2
Family Centroid CFAMM00321350 Functional Category Bioactive
Superfamily Translocator protein Binder Superfamily
Class Class 409

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A Ligand Melatonin Family 20 988
Nicotinic acetylcholine receptor Ligand AZD0328 Family 11 97
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 9 115
Nicotinic acetylcholine receptor Ligand Dianicline Family 6 13
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand WIN-5... 12 52
RAC-gamma serine/threonine-protein kinase Inhibitor A-443654 F... 67 59
Cytochrome P450 11B1, mitochondrial Inhibitor 5-(6-methoxynaph... 7 4
5-hydroxytryptamine receptor 2A and Amine oxidase [flavin-cont... 4 32
Fatty-acid amide hydrolase 1 Inhibitor Pyridin-3-yl 4-butoxybe... 10 5
Translocator protein Inhibitor 4-methoxy-5-phenyl-6-thia-10b-a... 7 32
Metabotropic glutamate receptor 5 Ligand 7-(3,5-dimethoxypheny... 2 7
Cannabinoid receptor 1 Ligand 1-(2-morpholinoethyl)-1h-indol-3... 8 46
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 8 32
Prelamin-A/C inhibitor 1-[(3,4-dimethoxyphenethyl)amino]-3-(1H... 1 2
Cellular tumor antigen p53 and DNA polymerase beta inhibitor C... 1 15
Translocator protein inhibitor SureCN6906757 family 3 2
Translocator protein inhibitor (4-chloro-6-phenylpyrrolo[2,1-d... 2 0
Reverse transcriptase/RNaseH inhibitor AC1L9TRY family 1 7
D(4) dopamine receptor and D(2) dopamine receptor ligand 1-(2-... 3 3
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 8 8
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 11 4
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 4
5-hydroxytryptamine receptor 6 ligand SureCN5498885 family 5 4
Translocator protein inhibitor 2-fluoro-N-[(2-methoxyphenyl)me... 8 27
Sodium-dependent serotonin transporter inhibitor AGN-PC-075G9A... 3 2
Neuronal acetylcholine receptor subunit alpha-2 and Neuronal a... 6 1
Translocator protein inhibitor N-methyl-2-(2-oxo-5-pyridin-4-y... 8 15
Egl nine homolog 1 inhibitor 2-(2-methoxy-4-phenylphenyl)-8-[(... 1 0
Cathepsin S and Cathepsin K inhibitor AGN-PC-078ZDC family 4 2
B2 bradykinin receptor and Cytochrome P450 3A4 ligand SureCN15... 4 0
Nischarin inhibitor SureCN7810370 family 1 0
5-hydroxytryptamine receptor 7 and 5-hydroxytryptamine recepto... 1 1


External ID

Functional Category

Molecule Name

CFAMM00321345 CHEMBL133144 Bioactive SureCN6907300
CFAMM00321333 CHEMBL135514 Bioactive SureCN4261481
CFAMM00321339 CHEMBL134282 Bioactive (6-phenylpyrrolo[2,1-d][1,5]benzoxazepin-7-yl) N-butyl-N-methylcarbamate
CFAMM00321351 CHEMBL135428 Bioactive [6-(3,5-difluorophenyl)pyrrolo[2,1-d][1,5]benzoxazepin-7-yl] N,N-diethylcarbamate
CFAMM00321344 CHEMBL134781 Bioactive [6-(3-methylphenyl)pyrrolo[2,1-d][1,5]benzoxazepin-7-yl] N,N-diethylcarbamate
CFAMM00321350 CHEMBL115740 Bioactive SureCN13502542
CFAMM00321338 CHEMBL135801 Bioactive (6-phenylpyrrolo[2,1-d][1,5]benzoxazepin-7-yl) N-propylcarbamate
CFAMM00321349 CHEMBL335085 Bioactive (6-phenylpyrrolo[2,1-d][1,5]benzoxazepin-7-yl) N-methyl-N-propylcarbamate
CFAMM00321337 CHEMBL132915 Bioactive (6-phenylpyrrolo[2,1-d][1,5]benzoxazepin-7-yl) azetidine-1-carboxylate
CFAMM00321342 CHEMBL117444 Bioactive [6-(4-methylphenyl)pyrrolo[2,1-d][1,5]benzoxazepin-7-yl] N,N-dimethylcarbamate
CFAMM00321348 CHEMBL325649 Bioactive SureCN6906358
CFAMM00321336 CHEMBL325025 Bioactive SureCN14435193
CFAMM00321354 CHEMBL341455 Bioactive SureCN14363884
CFAMM00321347 CHEMBL115470 Bioactive [6-(4-azidophenyl)pyrrolo[2,1-d][1,5]benzoxazepin-7-yl] N,N-dimethylcarbamate
CFAMM00321335 CHEMBL325169 Bioactive (6-phenylpyrrolo[2,1-d][1,5]benzoxazepin-7-yl) N,N-dimethylcarbamate
CFAMM00321341 CHEMBL326772 Bioactive SureCN6907858
CFAMM00321353 CHEMBL336774 Bioactive SureCN4259269
CFAMM00321334 CHEMBL135484 Bioactive [6-(3-methylphenyl)pyrrolo[2,1-d][1,5]benzoxazepin-7-yl] acetate
CFAMM00321340 CHEMBL326302 Bioactive O-(6-phenylpyrrolo[2,1-d][1,5]benzoxazepin-7-yl) N,N-diethylcarbamothioate
CFAMM00321352 CHEMBL445583 Bioactive (6-phenylpyrrolo[2,1-d][1,5]benzoxazepin-7-yl) N-cyclopropylcarbamate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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