CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12823
Family Name Proteasome subunit beta type-5 inhibitor (2R,3S)-3-[(2S)-butan-2-yl]-N-[(1S,2S)-2-[(2R)-2-[[(2S)-2-(naphthalene-2-carbonylamino)propanoyl]amino]-4-phenylbutyl]cyclopropyl]-4-oxooxetane-2-carboxamide family
No. of Seeds 1 No. of Other Members 9
Family Centroid CFAMM00418455 Functional Category Bioactive
Superfamily Kappa-type opioid receptor and Delta-type opioid receptor Binder Superfamily 6
Class Class 884

Cousin Family NamesSeedsMembers
Plasmepsin-2 Inhibitor PS-222036 Family 12 134
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 6 24
Cholecystokinin receptor type A Ligand CR-1795 Family 19 41
Cathepsin S inhibitor SureCN6857538 family 2 12
Proteasome subunit beta type-5 and Proteasome subunit beta typ... 1 0
Cathepsin K inhibitor 4-tert-butyl-N-[(2S)-4-methyl-1-oxo-1-[(... 1 3


External ID

Functional Category

Molecule Name

CFAMM00418455 CHEMBL2338319 Bioactive (2R,3S)-3-[(2S)-butan-2-yl]-N-[(1S,2S)-2-[(2R)-2-[[(2S)-2-(naphthalene-2-carbonylamino)propanoyl]amino]-4-phenylbutyl]cyclopropyl]-4-oxooxetane-2-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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