CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12840
Family Name 3-oxo-5-alpha-steroid 4-dehydrogenase 2 inhibitor 4-(benzyloxy)-1H-indole-2-carboxylic acid family
No. of Seeds 1 No. of Other Members 10
Family Centroid CFAMM00418509 Functional Category Bioactive with Natural Product
Superfamily Melatonin receptor type 1A and Melatonin receptor type 1B Binder Superfamily 3
Class Class 2976

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand monosubstituted indole derivat... 14 475
Cyclooxygenase Inhibitor Indomethacin Family 6 271
AP endonuclease APE1 Inhibitor 5-fluoro-1h-indole-2-carboxylic... 2 61
Integrin beta-3 Inhibitor L-756568 Family 8 59
Vascular endothelial growth factor receptor 1 Ligand Lycogarub... 6 292
Platelet-derived growth factor receptor alpha and Platelet-der... 4 54
Platelet-derived growth factor receptor alpha and Platelet-der... 2 13
Platelet-derived growth factor receptor beta and Receptor-type... 1 2
Metabotropic glutamate receptor 1 Ligand JNJ-16259685 Family 3 20
DNA topoisomerase 2-beta Inhibitor 3-(6-(furan-2-yl)-4-phenylp... 1 3
Prostaglandin G/H synthase 2 Inhibitor L-761000 Family 8 44
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 7 44
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 7 11
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 11 391
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 4 14
Histamine H3 receptor and Cytochrome P450 2D6 ligand AGN-PC-00... 18 32
Histamine H3 receptor ligand AGN-PC-00BG7Z family 11 49
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 10 50
Cellular tumor antigen p53 inhibitor CHEMBL1395699 family 1 30
D(3) dopamine receptor ligand N-[4-[4-(2,3-dichlorophenyl)pipe... 3 15
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 1 1
Histone deacetylase 3 and Histone deacetylase 9 inhibitor AGN-... 4 20
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 3 9
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 1 1
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 2 3
Glutamate receptor 2 and Glutamate receptor 4 ligand SureCN828... 1 0
Indoles Metabolite 7-Hydroxyheptaphylline Family 4 0
Indoles Metabolite Mukeic acid Family 1 1
Amino Acids and Derivatives Metabolite Flazine Family 3 2
Indoles Metabolite Koeniginequinone B Family 1 2
3-((4-methoxy-2-(methoxycarbonyl)-1H-indol-3-yl)carbamoyl)-2,2... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00418509 CHEMBL23399 Bioactive 4-(benzyloxy)-1H-indole-2-carboxylic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27029 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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