CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12845
Family Name Tyrosine-protein kinase JAK3 inhibitor CHEMBL234066 family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00418581 Functional Category Bioactive
Superfamily Coagulation factor X and Coagulation factor IX Binder Superfamily 4
Class Class 716

Cousin Family NamesSeedsMembers
High affinity nerve growth factor receptor Ligand Lestaurtinib... 6 126
B-lymphocyte antigen CD20 Inhibitor Rituxan Immunology Family 10 17
NF-kappa-B and Protein kinase C zeta type Inhibitor Go6976 Family 9 71
DNA topoisomerase 1 Inhibitor KT6006 Family 3 53
Vascular endothelial growth factor receptor 2 Ligand Isoindoli... 11 36
Vascular endothelial growth factor receptor 2 and Angiopoietin... 4 1
Protein kinase C alpha type and Protein kinase C delta type in... 4 37
Protein kinase C alpha type and Protein kinase C delta type in... 2 0


External ID

Functional Category

Molecule Name

CFAMM00418581 CHEMBL234066 Bioactive CHEMBL234066

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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