CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12848
Family Name Muscarinic acetylcholine receptor M2 and Muscarinic acetylcholine receptor M3 ligand AGN-PC-0769KK family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00417782 Functional Category Bioactive
Superfamily Muscarinic acetylcholine receptor M3 and Muscarinic acetylcholine receptor M2 Binder Superfamily
Class Class 4930

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand naphthol derivative Propranolo... 11 218
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Beta-1 adrenergic receptor Ligand Esmolol Family 5 39
Beta-1 adrenergic receptor Ligand Metoprolol Family 29 90
Beta adrenergic receptor Ligand Metipranolol Family 5 1
Beta-1 adrenergic receptor Ligand Oxprenolol Family 3 27
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Alpha adrenergic receptor Ligand Bevantolol Family 4 48
Beta-1 adrenergic receptor Ligand Nebivolol Family 5 22
5-hydroxytryptamine receptor 1A Ligand MN-305 Family 12 26
Histamine H3 receptor Ligand 4-isopropyl-2-(phenoxymethyl)morp... 4 10
Leukotriene A-4 hydrolase Inhibitor (r/s)-2-((4-phenoxyphenoxy... 7 18
D(4) dopamine receptor ligand AGN-PC-0073PO family 7 10
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 2 8
5-hydroxytryptamine receptor 1A and Sodium-dependent noradrena... 2 0
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 2 5
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 1 0
Beta-lactamase inhibitor CHEMBL1566697 family 1 5
Cytochrome P450 2D6 and Sodium channel protein type 1 subunit ... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00418586 CHEMBL234258 Bioactive AGN-PC-014SY5
CFAMM00418585 CHEMBL394137 Bioactive AGN-PC-0769KL

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26817 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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