CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12860
Family Name Coagulation factor X inhibitor 5-chloro-N-[(1R,2S)-2-[[4-[1-(pyrrolidin-1-ylmethyl)cyclopropyl]benzoyl]amino]cyclohexyl]thiophene-2-carboxamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00418626 Functional Category Bioactive
Superfamily Neuronal acetylcholine receptor subunit alpha-7 Ligand EVP-6124 Superfamily
Class Class 1214

Cousin Family NamesSeedsMembers
Neuronal acetylcholine receptor subunit alpha-7 Ligand EVP-612... 1 11
Substance-P receptor and Substance-K receptor ligand N-[(E,2R)... 1 1
Substance-K receptor ligand N-[1-[[(2S)-5-[4-(dimethylsulfamoy... 9 16
Growth hormone secretagogue receptor type 1 ligand SureCN76469... 4 4
Sigma non-opioid intracellular receptor 1 ligand ST50280143 fa... 3 54
Melanin-concentrating hormone receptor 1 ligand (3S)-3-[[5-(4-... 15 16
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 9 7
Melanin-concentrating hormone receptor 1 ligand (3S)-3-[[5-(2-... 5 1
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 6 6
Melanin-concentrating hormone receptor 1 ligand N-methyl-4-(4-... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 7 5
Kappa-type opioid receptor ligand 2-[2-oxo-2-[(2S)-2-(pyrrolid... 2 1
Sodium-dependent noradrenaline transporter and Sodium-dependen... 5 5
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 3 3
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 2 1
DNA-(apurinic or apyrimidinic site) lyase and Cytochrome P450 ... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00418626 CHEMBL234590 Bioactive 5-chloro-N-[(1R,2S)-2-[[4-[1-(pyrrolidin-1-ylmethyl)cyclopropyl]benzoyl]amino]cyclohexyl]thiophene-2-carboxamide
CFAMM00418627 CHEMBL450578 Bioactive SureCN8354712

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48688 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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