CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12870
Family Name Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial inhibitor (5S)-5-amino-7-hydroxy-2-phenyl-4,5-dihydropyrazolo[3,4-b]pyridin-6-one family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00418660 Functional Category Bioactive
Superfamily Prelamin-A/C and Histone deacetylase 1 Binder Superfamily 2
Class Class 1024

Cousin Family NamesSeedsMembers
RAC-gamma serine/threonine-protein kinase Inhibitor BMS-754807... 20 90
Prothrombin inhibitor 2-[(2S)-1-[(2R)-2-amino-3-phenylpropanoy... 3 16
Platelet-activating factor receptor ligand SureCN9384429 family 11 3
Serine/threonine-protein kinase D1 and Polycystin-2 inhibitor ... 3 7
Adenosine receptor A3 ligand N-(5-methyl-2-phenylpyrazolo[4,3-... 5 8
Adenosine receptor A2a ligand AGN-PC-077RWY family 4 5
Prothrombin and Survival motor neuron protein inhibitor CHEMBL... 2 14
Smoothened homolog inhibitor (8aS)-N-[2-(3-chlorophenyl)pyrazo... 2 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor (2... 16 5
Metabotropic glutamate receptor 5 ligand 5-(4-fluorophenyl)-1,... 7 1
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... 9 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00418660 CHEMBL2347108 Bioactive (5S)-5-amino-7-hydroxy-2-phenyl-4,5-dihydropyrazolo[3,4-b]pyridin-6-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26199 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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