CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12872
Family Name Beta-secretase 1 and Beta-secretase 2 inhibitor N-[3-[(4S)-2-amino-4-methyl-5,6-dihydro-1,3-oxazin-4-yl]-4-fluorophenyl]-5-chloropyridine-2-carboxamide family
No. of Seeds 6 No. of Other Members 4
Family Centroid CFAMM00411677 Functional Category Bioactive
Superfamily Beta-secretase 1 and Beta-secretase 2 Binder Superfamily 8
Class Class 913

Cousin Family NamesSeedsMembers
Glycogen phosphorylase, muscle form Inhibitor PSN357 Family 3 253
secretase Inhibitor LY2886721 Family 1 2
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 93
Prothrombin inhibitor SureCN7371121 family 13 3
Beta-secretase 1 and Potassium voltage-gated channel subfamily... 2 11
Coagulation factor X inhibitor 3-chloro-N-[(1S,2S)-2-[[4-(2-ox... 22 3
Beta-secretase 2 and Beta-secretase 1 inhibitor N-[3-[(1S,7S)-... 7 4
Beta-secretase 1 inhibitor N-[3-[(4R,5R,6S)-2-amino-5-fluoro-4... 4 11
Beta-secretase 1 and Beta-secretase 2 inhibitor SureCN14726714... 4 1
Beta-secretase 2 and Beta-secretase 1 inhibitor N-[6-[(4R)-2-a... 1 1
Poly [ADP-ribose] polymerase 1 inhibitor SureCN3553433 family 22 0
Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-07R9GP family 5 0
Beta-secretase 2 and Beta-secretase 1 inhibitor N-[3-[(4R)-2-a... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00418676 CHEMBL2403769 Bioactive SureCN1173499
CFAMM00418680 CHEMBL2403770 Bioactive SureCN1173421
CFAMM00418677 CHEMBL2403777 Bioactive SureCN2584678

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

42686 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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