CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12899
Family Name CX3C chemokine receptor 1 and C-X-C chemokine receptor type 2 ligand (2R)-2-[[2-amino-5-[(1S)-1-(2-fluorophenyl)ethyl]sulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol family
No. of Seeds 7 No. of Other Members 4
Family Centroid CFAMM00418859 Functional Category Bioactive
Superfamily C-X-C chemokine receptor type 2 and CX3C chemokine receptor 1 Binder Superfamily
Class Class 3854

Cousin Family NamesSeedsMembers
Mitogen-activated protein kinase 3 and RAF proto-oncogene seri... 8 5
CX3C chemokine receptor 1 and C-X-C chemokine receptor type 2 ... 2 5
CX3C chemokine receptor 1 and C-X-C chemokine receptor type 2 ... 1 22
C-X-C chemokine receptor type 2 and CX3C chemokine receptor 1 ... 6 18
Aurora kinase B and Tyrosine-protein kinase ITK/TSK inhibitor ... 2 2
Tyrosine-protein kinase ITK/TSK and Tyrosine-protein kinase Lc... 5 0
Tyrosine-protein kinase ITK/TSK and Tyrosine-protein kinase Lc... 2 2
C-X-C chemokine receptor type 2 ligand (2R)-2-[[7-amino-2-[(2,... 1 3
C-X-C chemokine receptor type 2 ligand 5-[(3-chloro-2-fluoroph... 2 0
C-X-C chemokine receptor type 2 ligand AGN-PC-03T2BW family 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00418858 CHEMBL429682 Bioactive N-[5-[(2,3-difluorophenyl)methylsulfanyl]-7-[[(2R)-1-hydroxypropan-2-yl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-2-yl]methanesulfonamide
CFAMM00418864 CHEMBL2349322 Bioactive (2R)-2-[[2-amino-5-[(2-bromophenyl)methylsulfanyl]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
CFAMM00418863 CHEMBL397237 Bioactive (2R)-2-[[2-amino-5-[(2,3-difluorophenyl)methylsulfanyl]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]propan-1-ol
CFAMM00418861 CHEMBL380732 Bioactive (2R)-2-[[2-amino-5-[(2,3-difluorophenyl)methylsulfanyl]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]butan-1-ol
CFAMM00418859 CHEMBL2349316 Bioactive (2R)-2-[[2-amino-5-[(1S)-1-(2-fluorophenyl)ethyl]sulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27285 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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