CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12912
Family Name Peroxisome proliferator-activated receptor delta and Peroxisome proliferator-activated receptor gamma ligand AGN-PC-076BJV family
No. of Seeds 7 No. of Other Members 5
Family Centroid CFAMM00418919 Functional Category Bioactive with Natural Product
Superfamily Beta-2 adrenergic receptor and Peroxisome proliferator-activated receptor gamma Binder Superfamily
Class Class 3172

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
Cyclooxygenase Inhibitor Indomethacin Family 6 271
Arachidonate 5-lipoxygenase Inhibitor MK-591 Family 9 161
Vascular endothelial growth factor receptor 1 Ligand Lycogarub... 6 292
Prostaglandin E2 receptor EP1 subtype Ligand GSK-345931A Family 5 14
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 7 44
Prostaglandin E2 receptor EP4 subtype and Prostaglandin D2 rec... 1 1
Histamine H3 receptor ligand AGN-PC-00BG7Z family 11 49
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 10 50
Glutamate receptor ionotropic, NMDA 1 ligand (3S)-3-[2-[4-(ami... 1 1
D(3) dopamine receptor ligand N-[4-[4-(2,3-dichlorophenyl)pipe... 3 15
D(2) dopamine receptor and Alpha-1B adrenergic receptor ligand... 3 4
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor 3-... 4 8
Glucagon receptor and Gastric inhibitory polypeptide receptor ... 2 5
Glucagon receptor ligand 3-[[4-[(2S)-2-[5-(trifluoromethoxy)-1... 1 2
Translocator protein inhibitor (4S)-N,N-diethyl-9-(2-fluoranyl... 9 10
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 1 1
Substance-P receptor ligand AGN-PC-01VLKE family 9 11
Prostaglandin D2 receptor 2 ligand 2-[5-chloro-3-[3-[2-(4-chlo... 1 2
Acetylcholinesterase and Cholinesterase inhibitor N-[5-[(6-chl... 4 2
Peroxisome proliferator-activated receptor delta and Peroxisom... 2 1
Histone deacetylase 3 and Histone deacetylase 9 inhibitor AGN-... 4 20
Cathepsin K inhibitor N-[(2S)-4-methyl-1-[2-[4-(2-methylpropox... 4 0
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 3 9
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 18000... 1 1
Gamma-aminobutyric acid receptor subunit pi and Gamma-aminobut... 2 10
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 2 0
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 6 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00418919 CHEMBL237277 Bioactive AGN-PC-076BJV
CFAMM00418926 CHEMBL235143 Bioactive SureCN4616277
CFAMM00418916 CHEMBL238357 Bioactive SureCN4617414
CFAMM00418923 CHEMBL399217 Bioactive AGN-PC-076BJZ

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27291 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543