CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12916
Family Name Melanocortin receptor 4 and Cytochrome P450 3A4 ligand 2-amino-N-[(1S)-1-[2-[4-[(2R)-3-(2,4-dichlorophenyl)-2-(2-oxopyrrolidin-1-yl)propanoyl]piperazin-1-yl]-5-fluorophenyl]-3-methylbutyl]acetamide family
No. of Seeds 52 No. of Other Members 12
Family Centroid CFAMM00418990 Functional Category Bioactive
Superfamily Melanocortin receptor 4 and Prelamin-A/C Binder Superfamily
Class Class 1375

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Sodium channel Ligand xylidine derivative Mepivacaine Family 10 114
Sodium channel protein type 5 subunit alpha Ligand Procainamid... 7 291
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 43 161
Glycine receptor subunit beta Ligand Gw 468816 Family 4 67
Neuromedin-K receptor Ligand Osanetant Family 38 192
Motilin receptor Ligand GSK962040 Family 30 457
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 11 67
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Vasopressin V2 receptor Ligand FR161282 Family 17 83
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 19 186
Prothrombin Inhibitor D-leucyl-n-(3-chlorobenzyl)-l-prolinamid... 18 168
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 19 88
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Bifunctional epoxide hydrolase 2 Inhibitor N-(3-chloro-phenyl)... 2 43
Cannabinoid receptor 1 Ligand 1-(bis(4-chlorophenyl)methyl)-3-... 4 44
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 7 35
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 3 26
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Phospholipase D1 Inhibitor Halopemide Family 17 111
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 1 1
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolin... 3 14
D(2) dopamine receptor Ligand PD-168077 Family 6 5
Aminopeptidase N Inhibitor N1-(4-chlorobenzyl)-2-benzyl-n3-hyd... 9 86
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Prothrombin and Plasminogen inhibitor [(1R)-5-amino-1-[[2-[N-(... 1 0
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
D(4) dopamine receptor and D(2) dopamine receptor ligand methy... 2 11
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 1 0
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07ZBI0 family 2 16
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 4 10
D(4) dopamine receptor and D(2) dopamine receptor ligand 2-[4-... 1 0
Substance-K receptor and Substance-P receptor ligand N-[4-[[4-... 1 4
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 1 1
72 kDa type IV collagenase and Stromelysin-1 inhibitor [(2S)-2... 9 6
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 4 6
E3 ubiquitin-protein ligase Mdm2 inhibitor (2'R,3R,3'S,5'S)-6-... 17 51
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 15 12
Melanocortin receptor 4 ligand tert-butyl 4-[(3S)-4-[4-[2-[1-[... 2 6
Melanocortin receptor 4 and Melanocortin receptor 5 ligand N-[... 16 117
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 4 0
Coagulation factor X inhibitor 3-amino-4-chloro-N-[(1R)-2-[4-(... 1 1
Lethal factor inhibitor (2R)-6-[(4-chlorophenyl)methylamino]-2... 3 0
P2X purinoceptor 7 inhibitor N-(1-adamantylmethyl)-5-amino-2-c... 3 4
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 3 6
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 2 7
D(3) dopamine receptor and Alpha-1B adrenergic receptor ligand... 11 8
Substance-P receptor ligand (2S,4S)-2-N-[3-(diethylamino)propy... 2 7
Cellular tumor antigen p53 and Inositol monophosphatase 1 inhi... 1 12
Prelamin-A/C and Lysine-specific demethylase 4E inhibitor 4-(4... 2 3
Squalene synthase inhibitor AGN-PC-09M2X2 family 12 22
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 24 11
Melanocortin receptor 4 and Melanocortin receptor 5 ligand AC1... 7 31
Ceramide glucosyltransferase and Cytochrome P450 3A4 inhibitor... 7 16
Melanocortin receptor 4 and Melanocortin receptor 5 ligand AC1... 5 37
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[[2-(2,4-dic... 4 9
Vasopressin V1a receptor ligand N-[(2R)-3-(4-chlorophenyl)-1-[... 6 0
Dipeptidyl peptidase 8 inhibitor (2S)-2-amino-4-[4-[bis(4-fluo... 2 9
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 8 1
Melanocortin receptor 4 ligand (3R)-N-[(2R)-3-(4-chlorophenyl)... 6 9
Neuropeptide Y receptor type 5 ligand 2-(6-chloro-3,4-dihydro-... 5 1
Melanin-concentrating hormone receptor 1 ligand 4-(4-chlorophe... 2 0
D(4) dopamine receptor ligand 1-Piperidineacetamide, 4-(2-cyan... 3 7
Melanocortin receptor 4 and Melanocortin receptor 5 ligand 3-[... 18 26
Lysosomal Pro-X carboxypeptidase inhibitor (2S,3S)-2-[(2-amino... 3 3
Baculoviral IAP repeat-containing protein 2 and E3 ubiquitin-p... 2 1
Oxytocin receptor ligand (2R)-2-[(2R,5R)-5-(2,3-dihydro-1H-ind... 2 0
C-C chemokine receptor type 1 ligand SureCN3159355 family 7 9
Melanocortin receptor 4 and Melanocortin receptor 5 ligand (3R... 6 1
D(2) dopamine receptor and Potassium voltage-gated channel sub... 1 1
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 8 4
Nociceptin receptor and Mu-type opioid receptor ligand N,N-dim... 5 4
Melanin-concentrating hormone receptor 1 and Potassium voltage... 2 2
Melanocortin receptor 4 ligand SureCN6183720 family 2 5
Microsomal triglyceride transfer protein large subunit inhibit... 8 1
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 11 9
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 3 0
Substance-P receptor and Substance-K receptor ligand AGN-PC-07... 5 2
Growth hormone secretagogue receptor type 1 ligand N-[4,6-dich... 2 0
Cathepsin K and Cathepsin B inhibitor (1R,2R)-N-(cyanomethyl)-... 1 6
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 4
Renin inhibitor (E)-but-2-enedioic acid;(3S,5R)-5-[4-(2-chloro... 14 5
P2X purinoceptor 7 inhibitor AGN-PC-050YNC family 1 6
P2X purinoceptor 7 inhibitor SureCN3726471 family 3 0
P2X purinoceptor 7 inhibitor AGN-PC-088GOO family 3 0
P2X purinoceptor 7 inhibitor AGN-PC-050YWL family 2 4
P2X purinoceptor 7 inhibitor SureCN3652462 family 5 2
P2X purinoceptor 7 inhibitor SureCN3721807 family 3 0
Melanin-concentrating hormone receptor 1 ligand 3-chloro-5-[4-... 2 0
Translocator protein inhibitor CHEMBL2332254 family 6 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 1
Melanocortin receptor 4 ligand N-[(1S)-1-[2-[4-[(3S,4R)-4-(4-c... 26 13
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 3
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 2 1
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 1 1
Nociceptin receptor and Delta-type opioid receptor ligand spir... 25 9
Melanin-concentrating hormone receptor 1 ligand SureCN5517533 ... 2 3
C-C chemokine receptor type 2 ligand 2-amino-N-[2-[[(3R)-1-[(4... 5 1
Sodium channel protein type 9 subunit alpha ligand tert-butyl ... 2 30
Melanocortin receptor 4 ligand N-[(1S)-1-[2-[4-[(2R,3R)-3-(4-c... 1 0
Melanocortin receptor 4 and Melanocortin receptor 5 ligand N-[... 6 0
Urotensin-2 receptor and Cytochrome P450 2D6 ligand 2-[3,4-dic... 2 3
C-C chemokine receptor type 2 ligand 2-amino-N-[2-[[(3R)-1-[(3... 2 4
Kappa-type opioid receptor and Urotensin-2 receptor ligand 2-(... 5 1
5-hydroxytryptamine receptor 7 ligand 3-ethyl-3-[4-[4-(4-fluor... 3 1
5-hydroxytryptamine receptor 7 ligand 7-chloro-3-[4-[4-(4-chlo... 2 0
Mu-type opioid receptor and Nociceptin receptor ligand SureCN8... 7 1
Substance-K receptor and Neuromedin-K receptor ligand 1-benzyl... 3 10
Oxytocin receptor ligand N-[1-[2-[[(2S)-1-amino-3-(3,4-dichlor... 1 0
Growth hormone secretagogue receptor type 1 ligand 2-amino-2-m... 4 2
Glutamate receptor ionotropic, NMDA 1 ligand CHEMBL40730 family 4 1
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 3 2
Sodium-dependent dopamine transporter and Transporter inhibito... 6 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor methyl ... 6 2
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 11 4
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 4 0
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 4 1
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 2 5
Sodium-dependent noradrenaline transporter inhibitor AGN-PC-07... 1 1
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 0
Progesterone receptor ligand CHEMBL403139 family 2 0
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 8
Melanocortin receptor 4 ligand 2-amino-N-[(2R)-3-(2,4-dichloro... 5 5
Melanocortin receptor 4 ligand NBI-12i family 1 0
Nociceptin receptor and Mu-type opioid receptor ligand (1R,5R)... 4 9
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 4 1
C-C chemokine receptor type 1 ligand (2R)-2-N-[(4-chlorophenyl... 1 1
Sodium-dependent noradrenaline transporter and Sodium-dependen... 1 0
72 kDa type IV collagenase and Disintegrin and metalloproteina... 1 5
Progesterone receptor ligand SureCN3031001 family 8 40
D(1A) dopamine receptor and D(3) dopamine receptor ligand 1-[4... 1 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 0
Potassium voltage-gated channel subfamily H member 2 and D(3) ... 3 0
C-C chemokine receptor type 5 ligand AC1MHPA7 family 2 2
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand (3R,6... 5 3
Cannabinoid receptor 1 ligand SureCN14463736 family 2 0
Sodium-dependent dopamine transporter and Sodium-dependent nor... 1 0
C-C chemokine receptor type 5 ligand AC1MHP8Y family 1 0
Voltage-dependent T-type calcium channel subunit alpha-1H liga... 3 4
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 4 6
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 3
Cathepsin S and Cathepsin L1 inhibitor arylaminoethyl amide de... 2 4
Transient receptor potential M8 protein ligand 1-[(2S)-2-(2-ch... 4 2
C-C chemokine receptor type 3 ligand 4-[[2-(4-chlorophenyl)eth... 4 2
Aldose reductase inhibitor Spiro-cimqat family 6 8
C5a anaphylatoxin chemotactic receptor 1 ligand SureCN12047568... 1 1
E3 ubiquitin-protein ligase Mdm2 inhibitor SureCN5171589 family 10 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00418964 CHEMBL393716 Bioactive 3-amino-N-[(2R)-1-[4-[2-[(1S)-1-amino-3-methylbutyl]-4-(trifluoromethyl)phenyl]piperazin-1-yl]-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl]propanamide
CFAMM00418977 CHEMBL236519 Bioactive 1-[(2R)-1-[4-[2-[(1S)-1-(2-aminoethylamino)-3-methylbutyl]-4-(trifluoromethyl)phenyl]piperazin-1-yl]-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl]pyrrolidin-2-one
CFAMM00418990 CHEMBL235421 Bioactive 2-amino-N-[(1S)-1-[2-[4-[(2R)-3-(2,4-dichlorophenyl)-2-(2-oxopyrrolidin-1-yl)propanoyl]piperazin-1-yl]-5-fluorophenyl]-3-methylbutyl]acetamide
CFAMM00418970 CHEMBL391028 Bioactive 3-amino-N-[(1S)-1-[2-[4-[(2R)-3-(2,4-dichlorophenyl)-2-(2-oxopyrrolidin-1-yl)propanoyl]piperazin-1-yl]phenyl]-3-methylbutyl]propanamide
CFAMM00418983 CHEMBL236839 Bioactive 2-amino-N-[(2R)-1-[4-[2-[(1S)-1-amino-3-methylbutyl]-6-(trifluoromethyl)phenyl]piperazin-1-yl]-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl]acetamide
CFAMM00418963 CHEMBL397582 Bioactive N-[(1S)-1-[2-[4-[(2R)-3-(2,4-dichlorophenyl)-2-(2-oxopyrrolidin-1-yl)propanoyl]piperazin-1-yl]phenyl]-3-methylbutyl]-3-(methylamino)propanamide
CFAMM00418976 CHEMBL237578 Bioactive 1-[(2R)-1-[4-[2-[(1S)-1-(3-aminopropylamino)-3-methylbutyl]phenyl]piperazin-1-yl]-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl]pyrrolidin-2-one
CFAMM00418956 CHEMBL235190 Bioactive N-[(2R)-1-[4-[2-[(1S)-1-amino-3-methylbutyl]-4-(trifluoromethyl)phenyl]piperazin-1-yl]-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl]piperidine-4-carboxamide
CFAMM00418982 CHEMBL391427 Bioactive N-[(2R)-1-[4-[2-[(1S)-1-amino-3-methylbutyl]-6-fluorophenyl]piperazin-1-yl]-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl]acetamide
CFAMM00418995 CHEMBL237268 Bioactive 2-amino-N-[(2R)-1-[4-[2-[(1R)-1-amino-3-methylbutyl]-6-fluorophenyl]piperazin-1-yl]-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl]acetamide
CFAMM00418962 CHEMBL397583 Bioactive N-[(1S)-1-[2-[4-[(2R)-3-(2,4-dichlorophenyl)-2-(2-oxopyrrolidin-1-yl)propanoyl]piperazin-1-yl]-5-methylphenyl]-3-methylbutyl]-3-(methylamino)propanamide
CFAMM00418975 CHEMBL488030 Bioactive N-[(2R)-1-[4-[2-(1-amino-3-methylbutyl)phenyl]piperazin-1-yl]-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl]-2-methyl-2-(methylamino)propanamide
CFAMM00419001 CHEMBL235640 Bioactive N-[(1S)-1-[2-[4-[(2R)-3-(2,4-dichlorophenyl)-2-(2-oxopyrrolidin-1-yl)propanoyl]piperazin-1-yl]phenyl]-3-methylbutyl]-2-(methylamino)acetamide
CFAMM00418955 CHEMBL393204 Bioactive 1-[(2R)-3-(2,4-dichlorophenyl)-1-[4-[2-[(1S)-3-methyl-1-[2-(methylamino)ethylamino]butyl]phenyl]piperazin-1-yl]-1-oxopropan-2-yl]pyrrolidin-2-one
CFAMM00418968 CHEMBL524443 Bioactive N-[(1S)-1-[2-[4-[(2R)-3-(2,4-dichlorophenyl)-2-methylpropanoyl]piperazin-1-yl]-3-fluorophenyl]-2-methylpropyl]-2-(methylamino)acetamide
CFAMM00418981 CHEMBL237050 Bioactive 3-amino-N-[(2R)-1-[4-[2-[(1S)-1-amino-3-methylbutyl]-6-(trifluoromethyl)phenyl]piperazin-1-yl]-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl]propanamide
CFAMM00418994 CHEMBL237266 Bioactive N-[(2R)-1-[4-[2-[(1R)-1-amino-3-methylbutyl]-6-fluorophenyl]piperazin-1-yl]-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl]acetamide
CFAMM00418961 CHEMBL397580 Bioactive 3-amino-N-[(1S)-1-[2-[4-[(2R)-3-(2,4-dichlorophenyl)-2-(2-oxopyrrolidin-1-yl)propanoyl]piperazin-1-yl]-3-fluorophenyl]-3-methylbutyl]propanamide
CFAMM00418974 CHEMBL262321 Bioactive (2R)-2-amino-N-[(1S)-1-[2-[4-[(2R)-3-(2,4-dichlorophenyl)-2-(2-oxopyrrolidin-1-yl)propanoyl]piperazin-1-yl]-5-methylphenyl]-3-methylbutyl]propanamide
CFAMM00418987 CHEMBL487044 Bioactive N-[(2R)-1-[4-[2-(1-amino-3-methylbutyl)phenyl]piperazin-1-yl]-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl]-2-(methylamino)acetamide
CFAMM00418954 CHEMBL237146 Bioactive 1-[(2R)-3-(2,4-dichlorophenyl)-1-[4-[2-[(1S)-1-(diethylamino)-3-methylbutyl]-6-fluorophenyl]piperazin-1-yl]-1-oxopropan-2-yl]pyrrolidin-2-one
CFAMM00418967 CHEMBL236520 Bioactive 3-amino-N-[(1S)-1-[2-[4-[(2R)-3-(2,4-dichlorophenyl)-2-(2-oxopyrrolidin-1-yl)propanoyl]piperazin-1-yl]-5-fluorophenyl]-3-methylbutyl]propanamide
CFAMM00418980 CHEMBL402075 Bioactive N-[(1S)-1-[2-[4-[(3S,4R)-4-(2,4-dichlorophenyl)-1-propan-2-ylpyrrolidine-3-carbonyl]piperazin-1-yl]-3-fluorophenyl]-2-methylpropyl]-3-(dimethylamino)propanamide
CFAMM00418993 CHEMBL237267 Bioactive 2-amino-N-[(2R)-1-[4-[2-[(1S)-1-amino-3-methylbutyl]-6-fluorophenyl]piperazin-1-yl]-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl]acetamide
CFAMM00418960 CHEMBL397581 Bioactive 3-amino-N-[(1S)-1-[2-[4-[(2R)-3-(2,4-dichlorophenyl)-2-(2-oxopyrrolidin-1-yl)propanoyl]piperazin-1-yl]-5-(trifluoromethyl)phenyl]-3-methylbutyl]propanamide
CFAMM00418973 CHEMBL528108 Bioactive 2-amino-N-[(2R)-1-[4-[2-(1-amino-3-methylbutyl)phenyl]piperazin-1-yl]-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl]-2-methylpropanamide
CFAMM00418986 CHEMBL487043 Bioactive 2-amino-N-[(2R)-1-[4-[2-(1-amino-3-methylbutyl)phenyl]piperazin-1-yl]-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl]acetamide
CFAMM00418999 CHEMBL412023 Bioactive N-[(1S)-1-[2-[4-[(2R)-3-(2,4-dichlorophenyl)-2-(2-oxopyrrolidin-1-yl)propanoyl]piperazin-1-yl]-5-methylphenyl]-3-methylbutyl]-2-(methylamino)acetamide
CFAMM00418953 CHEMBL441136 Bioactive N-[(1S)-1-[2-[4-[(2R)-3-(2,4-dichlorophenyl)-2-(2-oxopyrrolidin-1-yl)propanoyl]piperazin-1-yl]-5-fluorophenyl]-3-methylbutyl]-2-(methylamino)acetamide
CFAMM00418966 CHEMBL393788 Bioactive 1-[(2R)-1-[4-[2-[(1S)-1-(3-aminopropylamino)-3-methylbutyl]-6-fluorophenyl]piperazin-1-yl]-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl]pyrrolidin-2-one
CFAMM00418979 CHEMBL236423 Bioactive N-[(2R)-1-[4-[2-[(1S)-1-amino-3-methylbutyl]-4-(trifluoromethyl)phenyl]piperazin-1-yl]-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl]acetamide
CFAMM00419005 CHEMBL438683 Bioactive 1-[(2R)-1-[4-[2-[(1S)-1-(3-aminopropylamino)-3-methylbutyl]-4-(trifluoromethyl)phenyl]piperazin-1-yl]-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl]pyrrolidin-2-one
CFAMM00418992 CHEMBL236064 Bioactive 1-[(2R)-1-[4-[2-[(1S)-1-amino-2-methylpropyl]-4-(trifluoromethyl)phenyl]piperazin-1-yl]-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl]pyrrolidin-2-one
CFAMM00418959 CHEMBL397584 Bioactive N-[(1S)-1-[2-[4-[(2R)-3-(2,4-dichlorophenyl)-2-(2-oxopyrrolidin-1-yl)propanoyl]piperazin-1-yl]phenyl]-3-methylbutyl]-3-(dimethylamino)propanamide
CFAMM00418985 CHEMBL488710 Bioactive (2S)-2-amino-N-[(2R)-1-[4-[2-(1-amino-3-methylbutyl)phenyl]piperazin-1-yl]-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl]propanamide
CFAMM00418965 CHEMBL236625 Bioactive 3-amino-N-[(2R)-1-[4-[2-[(1R)-1-amino-3-methylbutyl]-4-(trifluoromethyl)phenyl]piperazin-1-yl]-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl]propanamide
CFAMM00418978 CHEMBL236424 Bioactive 2-amino-N-[(2R)-1-[4-[2-[(1S)-1-amino-3-methylbutyl]-4-(trifluoromethyl)phenyl]piperazin-1-yl]-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl]acetamide
CFAMM00418991 CHEMBL236015 Bioactive 3-amino-N-[(2R)-1-[4-[2-[(1R)-1-amino-3-methylbutyl]-6-fluorophenyl]piperazin-1-yl]-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl]propanamide
CFAMM00419004 CHEMBL396884 Bioactive 1-[(2R)-3-(2,4-dichlorophenyl)-1-[4-[2-[(1S)-1-(2-hydroxyethylamino)-3-methylbutyl]-4-(trifluoromethyl)phenyl]piperazin-1-yl]-1-oxopropan-2-yl]pyrrolidin-2-one
CFAMM00418958 CHEMBL396434 Bioactive (2R)-2-amino-N-[(1S)-1-[2-[4-[(2R)-3-(2,4-dichlorophenyl)-2-(2-oxopyrrolidin-1-yl)propanoyl]piperazin-1-yl]-5-fluorophenyl]-3-methylbutyl]propanamide
CFAMM00418997 CHEMBL236939 Bioactive 1-[(2R)-1-[4-[2-[(1S)-1-amino-3-methylbutyl]-4-methylphenyl]piperazin-1-yl]-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl]pyrrolidin-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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