CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12923
Family Name P2X purinoceptor 7 inhibitor N-(1-adamantylmethyl)-2-chloro-5-[(3R)-piperidin-3-yl]oxybenzamide family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00419045 Functional Category Bioactive
Superfamily P2X purinoceptor 7 and Pol polyprotein Binder Superfamily
Class Class 2895

Cousin Family NamesSeedsMembers
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Urotensin-2 receptor Ligand SB-436811 Family 6 71
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
P2X purinoceptor 7 inhibitor N-(1-adamantylmethyl)-2-chloro-5-... 1 1
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 7 9
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 6 16
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 0
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 15
Survival motor neuron protein and Muscleblind-like protein 1 i... 1 10
Potassium voltage-gated channel subfamily H member 2 ligand me... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00419045 CHEMBL235357 Bioactive N-(1-adamantylmethyl)-2-chloro-5-[(3R)-piperidin-3-yl]oxybenzamide
CFAMM00419044 CHEMBL340983 Bioactive N-(1-adamantylmethyl)-2-chloro-5-methoxybenzamide
CFAMM00419046 CHEMBL235579 Bioactive N-(1-adamantylmethyl)-2-chloro-5-[(3S)-piperidin-3-yl]oxybenzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27744 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543