CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12924
Family Name Disintegrin and metalloproteinase domain-containing protein 17 and 72 kDa type IV collagenase inhibitor AGN-PC-046EBA family
No. of Seeds 7 No. of Other Members 5
Family Centroid CFAMM00419057 Functional Category Bioactive
Superfamily Disintegrin and Cathepsin K Binder Superfamily
Class Class 2519

Cousin Family NamesSeedsMembers
Mannose-6-phosphate isomerase Inhibitor Sulfacetamide Family 19 117
5-hydroxytryptamine receptor 1A and Sigma non-opioid intracell... 7 28
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-morp... 6 81
5-hydroxytryptamine receptor 2A Ligand Cinanserin Family 3 27
Collagenase 3 and 72 kDa type IV collagenase inhibitor AGN-PC-... 5 31
Collagenase 3 and 72 kDa type IV collagenase inhibitor AGN-PC-... 7 2
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 2 0
Collagenase 3 and Stromelysin-1 inhibitor AGN-PC-02YH4D family 1 0
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,4-dimethylphen... 4 8
Disintegrin and metalloproteinase domain-containing protein 17... 2 0
Disintegrin and metalloproteinase domain-containing protein 17... 1 0
Peptide deformylase inhibitor AGN-PC-073KFH family 6 8
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 1 1


External ID

Functional Category

Molecule Name

CFAMM00419048 CHEMBL237467 Bioactive AGN-PC-04SS9G
CFAMM00419054 CHEMBL236573 Bioactive Tert-Butyl 4-({[4-(But-2-Yn-1-Ylamino)phenyl]sulfonyl}methyl)-4-[(Hydroxyamino)carbonyl]piperidine-1-Carboxylate
CFAMM00419047 CHEMBL236574 Bioactive AGN-PC-04SS9D
CFAMM00419053 CHEMBL400430 Bioactive AGN-PC-04SS9K
CFAMM00419052 CHEMBL399400 Bioactive AGN-PC-04SS9E
CFAMM00419058 CHEMBL399401 Bioactive AGN-PC-04SS9I
CFAMM00419057 CHEMBL235559 Bioactive AGN-PC-046EBA

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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