CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12926
Family Name Beta-2 adrenergic receptor ligand SureCN5346426 family
No. of Seeds 8 No. of Other Members 0
Family Centroid CFAMM00419072 Functional Category Bioactive
Superfamily Beta-2 adrenergic receptor and Peroxisome proliferator-activated receptor gamma Binder Superfamily
Class Class 3172

Cousin Family NamesSeedsMembers
HIV protease Inhibitor Saquinavir Family 64 428
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
Gastrin/cholecystokinin type B receptor ligand oligopeptide Ce... 35 209
Somatostatin receptor type 2 ligand octapeptide Lanreotide Family 93 156
ostatin receptor 5 Ligand Pasireotide Diaspartate Family 11 151
Cholecystokinin receptor type A Ligand A-71378 Family 77 23
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Plasminogen and Prothrombin Inhibitor 2-(2-hydroxy-phenyl)-1h-... 3 69
Oestrogen receptor and Estrogen receptor beta Ligand 4-(3-phen... 5 14
Serine/threonine-protein kinase Chk1 Inhibitor A-432411 Family 4 70
Delta-type opioid receptor and Gastrin/cholecystokinin type B ... 19 0
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-366... 5 75
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 46 0
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 6 0
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 3 28
Pol polyprotein inhibitor N-[(2S)-1-[[(2S,3R,4S,5S)-3,4-dihydr... 2 0
Vascular endothelial growth factor receptor 2 ligand indolyl q... 4 3
Somatostatin receptor type 5 and Somatostatin receptor type 1 ... 2 8
Renin inhibitor SureCN1144364 family 3 15
Histamine H3 receptor ligand AGN-PC-00BG7Z family 11 49
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 10 50
Glutamate receptor ionotropic, NMDA 2D and Glutamate receptor ... 2 21
Poly [ADP-ribose] polymerase 1 inhibitor SureCN5002485 family 2 11
Cannabinoid receptor 2 ligand [(4R,4aS,8aR)-4-hydroxy-4-phenyl... 2 41
Acetylcholinesterase inhibitor CHEMBL1651140 family 4 4
Substance-P receptor ligand 1-[4-(2-methoxyphenyl)piperazin-1-... 11 12
Transient receptor potential cation channel subfamily V member... 1 5
Beta-2 adrenergic receptor ligand SureCN4598646 family 7 7
Estrogen receptor and Estrogen receptor beta ligand N-[(2R)-4-... 7 11
Gonadotropin-releasing hormone receptor ligand SureCN7905635 f... 2 2
Histone deacetylase 3 and Histone deacetylase 9 inhibitor AGN-... 4 20
Cathepsin K inhibitor N-[(2S)-4-methyl-1-[2-[4-(2-methylpropox... 4 0
Coagulation factor X and Prothrombin inhibitor SureCN6434488 f... 3 13
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 4 4


External ID

Functional Category

Molecule Name

CFAMM00419066 CHEMBL235612 Bioactive SureCN4599051
CFAMM00419072 CHEMBL392056 Bioactive SureCN5346426
CFAMM00419065 CHEMBL236041 Bioactive SureCN4597291
CFAMM00419071 CHEMBL236040 Bioactive SureCN4598669
CFAMM00419070 CHEMBL391946 Bioactive SureCN14220446
CFAMM00419069 CHEMBL394339 Bioactive SureCN4598562
CFAMM00419068 CHEMBL235818 Bioactive SureCN5338548
CFAMM00419067 CHEMBL236251 Bioactive SureCN5342844

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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