CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12937
Family Name Substance-P receptor ligand (3R,4S)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-methyl-1-(5-methylpyrazine-2-carbonyl)-4-phenylpyrrolidine-3-carboxamide family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00419150 Functional Category Bioactive
Superfamily Substance-P receptor Ligand TAK-637 Superfamily
Class Class 840

Cousin Family NamesSeedsMembers
26S proteasome Inhibitor Bortezomib Family 7 65
Cannabinoid receptor 1 Ligand N-phenyl-5,6-dip-tolylpyrazine-2... 11 26
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor Di... 2 3
Protease inhibitor (3aS,6aR)-N-(1-anilino-1,2-dioxohexan-3-yl)... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00419150 CHEMBL238220 Bioactive (3R,4S)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-methyl-1-(5-methylpyrazine-2-carbonyl)-4-phenylpyrrolidine-3-carboxamide
CFAMM00419148 CHEMBL235882 Bioactive (3R,4S)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-4-(4-fluoro-2-methylphenyl)-N-methyl-1-(5-methylpyrazine-2-carbonyl)pyrrolidine-3-carboxamide
CFAMM00419146 CHEMBL393746 Bioactive (3R,4S)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-methyl-4-phenyl-1-(pyrazine-2-carbonyl)pyrrolidine-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27273 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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