CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12946
Family Name Beta-2 adrenergic receptor ligand SureCN4598646 family
No. of Seeds 7 No. of Other Members 7
Family Centroid CFAMM00419244 Functional Category Bioactive with Natural Product
Superfamily Beta-2 adrenergic receptor and Peroxisome proliferator-activated receptor gamma Binder Superfamily
Class Class 3172

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Vascular endothelial growth factor receptor 1 Ligand Lycogarub... 6 292
Platelet-derived growth factor receptor alpha and Platelet-der... 2 13
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Adenosine receptor A1 and Adenosine receptor A2a Ligand SB-298... 53 320
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-366... 5 75
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 7 44
Cathepsin K and Cathepsin S inhibitor dipeptidyl nitrile, 16f ... 3 18
Vascular endothelial growth factor receptor 2 ligand indolyl q... 4 3
Vascular endothelial growth factor receptor 2 ligand indolyl q... 2 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 8 32
Somatostatin receptor type 5 and Somatostatin receptor type 1 ... 2 8
Histamine H3 receptor ligand AGN-PC-00BG7Z family 11 49
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 10 50
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 6
Glutamate receptor ionotropic, NMDA 2D and Glutamate receptor ... 2 21
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 3 3
Cellular tumor antigen p53 inhibitor CHEMBL1395699 family 1 30
Poly [ADP-ribose] polymerase 1 inhibitor SureCN5002485 family 2 11
Translocator protein inhibitor N-(4-methoxyphenyl)-N,3-dimethy... 2 2
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 15
Cannabinoid receptor 2 ligand [(4R,4aS,8aR)-4-hydroxy-4-phenyl... 2 41
D(3) dopamine receptor ligand N-[4-[4-(2,3-dichlorophenyl)pipe... 3 15
Acetylcholinesterase inhibitor CHEMBL1651140 family 4 4
Cannabinoid receptor 1 ligand 5-cyano-N-(3-hydroxy-2,2-dimethy... 17 4
Coagulation factor X and Trypsin-1 inhibitor AGN-PC-0759OR family 4 7
NS5B protein inhibitor AGN-PC-00A17Z family 1 23
Histone deacetylase 3 and Histone deacetylase 9 inhibitor (3S,... 1 16
Vascular endothelial growth factor receptor 2 and Vascular end... 2 52
Substance-P receptor ligand (3R)-4-[3,5-bis(trifluoromethyl)be... 2 3
Substance-P receptor ligand 1-[4-(2-methoxyphenyl)piperazin-1-... 11 12
Plasmepsin-2 and Cathepsin D inhibitor 4-[4-[[(2S,3S)-1-[[(3S,... 3 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 159
Beta-2 adrenergic receptor ligand SureCN5346426 family 8 0
Estrogen receptor and Estrogen receptor beta ligand N-[(2R)-4-... 7 11
Vitamin D3 receptor ligand 1-ethyl-5-[3-[4-(2-hydroxy-3,3-dime... 2 2
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 1 1
Gonadotropin-releasing hormone receptor ligand SureCN7905635 f... 2 2
Histone deacetylase 3 and Histone deacetylase 9 inhibitor AGN-... 4 20
Mu-type opioid receptor ligand MITRAGYNINE family 2 8
Substance-P receptor ligand (4R)-N-[(2R)-1-[benzyl(methyl)amin... 1 4
Cathepsin K inhibitor N-[(2S)-4-methyl-1-[2-[4-(2-methylpropox... 4 0
Coagulation factor X and Prothrombin inhibitor SureCN6434488 f... 3 13
Interstitial collagenase and Matrilysin inhibitor (3S,6R,7S)-N... 2 4
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 3 9
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL4... 6 2
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 4 4
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 2 3
Mitogen-activated protein kinase 14 inhibitor SureCN4508019 fa... 1 0
Signal transducer and activator of transcription 1-alpha/beta ... 1 36
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 1 0
Potassium voltage-gated channel subfamily A member 5 ligand AG... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00419243 CHEMBL236042 Bioactive SureCN4598429
CFAMM00419242 CHEMBL391308 Bioactive SureCN4598379
CFAMM00419240 CHEMBL238347 Bioactive SureCN5337086
CFAMM00419239 CHEMBL237709 Bioactive SureCN4598115
CFAMM00419245 CHEMBL428027 Bioactive SureCN4599479
CFAMM00419228 CHEMBL236039 Bioactive SureCN4598866
CFAMM00419244 CHEMBL237501 Bioactive SureCN4598646

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26240 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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