CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12960
Family Name Motilin receptor ligand SureCN2768193 family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00419304 Functional Category Bioactive
Superfamily Delta-type opioid receptor and Mu-type opioid receptor Ligand 6-(2-phenethylisoindolin-5-yloxy)nicotinamide Superfamily
Class Class 2449

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase B-raf inhibitor diaryl urea an... 12 93
Histamine H3 receptor Ligand GSK239512 Family 2 65
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
5-hydroxytryptamine receptor 1B Ligand GR55562 Family 3 45
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
Cannabinoid receptor 2 Ligand JWH-202 Family 9 172
C-X-C chemokine receptor type 3 Ligand AMG-487 Family 28 73
Mu-type opioid receptor Ligand 6-(4-(2-(benzylamino)ethyl)phen... 3 27
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 8 57
Bifunctional epoxide hydrolase 2 Inhibitor N-benzyl-6-(3,3,3-t... 21 62
Reverse transcriptase/RNaseH inhibitor AC1LALKM family 2 19
Histamine H3 receptor and Potassium voltage-gated channel subf... 5 2
Histamine H3 receptor ligand SureCN3057575 family 4 3
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 2
Neuronal acetylcholine receptor subunit beta-4 and Neuronal ac... 1 0
Somatostatin receptor type 5 ligand AGN-PC-080TDB family 10 14
Somatostatin receptor type 5 ligand AGN-PC-088VSK family 2 3
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Bifunctional epoxide hydrolase 2 inhibitor SureCN3216677 family 4 9
Potassium voltage-gated channel subfamily H member 2 and Kappa... 5 33
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 6
Sodium channel protein type 10 subunit alpha and Sodium channe... 1 1
Sodium channel protein type 10 subunit alpha and Sodium channe... 3 22
Cellular tumor antigen p53 and DNA polymerase beta inhibitor C... 1 15
D(2) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 6 22
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 4 11
Survival motor neuron protein and Lysine-specific demethylase ... 1 1
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 2 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 3 21
Mitogen-activated protein kinase 14 inhibitor 3-fluoro-N-[4-me... 2 5
Ceramide glucosyltransferase and Cytochrome P450 3A4 inhibitor... 10 15
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 7
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 1 13
C-C chemokine receptor type 5 ligand 3,5-dichloro-N-[3-[4-[N-[... 2 6
C-C chemokine receptor type 5 ligand N-[(3R)-3-[4-[4-methoxy-N... 13 1
C-C chemokine receptor type 5 ligand 6-cyano-N-[(3R)-3-[4-[N-[... 3 0
Growth hormone secretagogue receptor type 1 and Potassium volt... 2 0
5-hydroxytryptamine receptor 1A and Alpha-1D adrenergic recept... 3 0
Beta-1 adrenergic receptor ligand N-[2-[[(2S)-3-(2-cyanophenox... 2 1
Histamine H3 receptor ligand 6-[[2-[2-[(2R)-2-methylpyrrolidin... 2 0
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 12 0
G-protein coupled bile acid receptor 1 ligand (4-cyclopropyl-2... 10 13
G-protein coupled bile acid receptor 1 ligand (4-cyclopropyl-2... 2 1
Motilin receptor ligand SureCN2765637 family 1 1
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Potassium voltage-gated channel subfamily KQT member 2 ligand ... 3 4
Glutamate receptor ionotropic, NMDA 2B ligand SureCN5532501 fa... 1 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 2
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 1 0
Macrophage colony-stimulating factor 1 receptor ligand AGN-PC-... 1 3
Alpha-2C adrenergic receptor and Alpha-2B adrenergic receptor ... 6 1
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 1
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 3 3
Reverse transcriptase/RNaseH inhibitor 7CN-6Et-9Me-PBOA-5one f... 4 1
Thromboxane-A synthase and Platelet-activating factor receptor... 1 6
NP N-(2-(2-methoxyphenyl)-4-oxo-4h-chromen-6-yl)nicotinamide F... 9 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00419305 CHEMBL2364317 Bioactive SureCN2765832
CFAMM00419304 CHEMBL2364295 Bioactive SureCN2768193

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27038 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543