CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1298
Family Name Muscarinic acetylcholine receptor M2 ligand AGN-PC-074ITY family
No. of Seeds 16 No. of Other Members 0
Family Centroid CFAMM00321697 Functional Category Bioactive
Superfamily Muscarinic acetylcholine receptor M2 Binder Superfamily
Class Class 3235

Cousin Family NamesSeedsMembers
Histamine H3 receptor Ligand A-349821 Family 49 228
Muscarinic acetylcholine receptor M2 ligand [4-[(3R)-4-[(1S)-1... 3 13
Muscarinic acetylcholine receptor M2 ligand (2-chlorophenyl)-[... 7 3
Muscarinic acetylcholine receptor M2 ligand AGN-PC-0745OX family 2 0
Muscarinic acetylcholine receptor M2 ligand AGN-PC-074ZZ3 family 11 1
Muscarinic acetylcholine receptor M2 ligand [4-[(3R)-4-[(1S)-1... 9 4
Muscarinic acetylcholine receptor M2 ligand (2R)-1-[(1S)-1-[4-... 10 2
Muscarinic acetylcholine receptor M2 ligand [4-[(3R)-4-[(1S)-1... 4 0
Muscarinic acetylcholine receptor M2 ligand N-[2-[4-[(3R)-4-[(... 2 0
Muscarinic acetylcholine receptor M2 ligand [4-[(3R)-4-[(1S)-1... 2 0
Muscarinic acetylcholine receptor M2 ligand [4-[(3R)-4-[(1S)-1... 3 0
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 7 1
Muscarinic acetylcholine receptor M2 ligand AGN-PC-074P5J family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00321683 CHEMBL308787 Bioactive AGN-PC-074IMA
CFAMM00321696 CHEMBL323850 Bioactive (2-methoxyphenyl)-[4-[4-[2-[4-(4-methoxyphenyl)sulfonylphenyl]-1,3-dioxolan-2-yl]piperidin-1-yl]piperidin-1-yl]methanone
CFAMM00321689 CHEMBL309720 Bioactive AGN-PC-074ITW
CFAMM00321695 CHEMBL305693 Bioactive AGN-PC-074IMQ
CFAMM00321688 CHEMBL117817 Bioactive [4-[4-[2-[4-(4-methoxyphenyl)sulfonylphenyl]-1,3-dioxolan-2-yl]piperidin-1-yl]piperidin-1-yl]-[2-(trifluoromethyl)phenyl]methanone
CFAMM00321694 CHEMBL116781 Bioactive (2,3-dimethylphenyl)-[4-[4-[2-[4-(4-methoxyphenyl)sulfonylphenyl]-1,3-dioxolan-2-yl]piperidin-1-yl]piperidin-1-yl]methanone
CFAMM00321687 CHEMBL78131 Bioactive AGN-PC-074ITX
CFAMM00321693 CHEMBL75108 Bioactive AGN-PC-074IR4
CFAMM00321686 CHEMBL72932 Bioactive AGN-PC-074IMB
CFAMM00321692 CHEMBL324832 Bioactive (2-fluorophenyl)-[4-[4-[2-[4-(4-methoxyphenyl)sulfonylphenyl]-1,3-dioxolan-2-yl]piperidin-1-yl]piperidin-1-yl]methanone
CFAMM00321698 CHEMBL119168 Bioactive (2-bromophenyl)-[4-[4-[2-[4-(4-methoxyphenyl)sulfonylphenyl]-1,3-dioxolan-2-yl]piperidin-1-yl]piperidin-1-yl]methanone
CFAMM00321685 CHEMBL116777 Bioactive [4-[4-[2-[4-(4-methoxyphenyl)sulfonylphenyl]-1,3-dioxolan-2-yl]piperidin-1-yl]piperidin-1-yl]-(2-methylphenyl)methanone
CFAMM00321691 CHEMBL311099 Bioactive (5-bromonaphthalen-1-yl)-[4-[4-[2-[4-(4-methoxyphenyl)sulfonylphenyl]-1,3-dioxolan-2-yl]piperidin-1-yl]piperidin-1-yl]methanone
CFAMM00321684 CHEMBL74141 Bioactive (4-fluoronaphthalen-1-yl)-[4-[4-[2-[4-(4-methoxyphenyl)sulfonylphenyl]-1,3-dioxolan-2-yl]piperidin-1-yl]piperidin-1-yl]methanone
CFAMM00321697 CHEMBL308166 Bioactive AGN-PC-074ITY
CFAMM00321690 CHEMBL115807 Bioactive [4-[4-[2-[4-(4-methoxyphenyl)sulfinylphenyl]-1,3-dioxolan-2-yl]piperidin-1-yl]piperidin-1-yl]-(2-methylphenyl)methanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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