CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12987
Family Name Sodium-dependent serotonin transporter and Histamine H3 receptor ligand AGN-PC-04F7KX family
No. of Seeds 6 No. of Other Members 4
Family Centroid CFAMM00147916 Functional Category Bioactive
Superfamily Sodium-dependent serotonin transporter and P2X purinoceptor 7 Binder Superfamily
Class Class 198

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Amyloid beta A4 protein Inhibitor Florbetapir F-18 Family 8 265
Nicotinic acetylcholine receptor Ligand AZD0328 Family 11 97
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 9 115
Apricoxib family 8 77
Nicotinic acetylcholine receptor Ligand Dianicline Family 6 13
Tissue-type plasminogen activator Inhibitor N-(7-benzyloxy-iso... 4 37
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Estradiol 17-beta-dehydrogenase 1 Inhibitor 4'-(6-methoxypyrid... 5 34
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 12 3
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 6
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 4 35
Squalene synthase Inhibitor ER-119884 Family 2 3
Cytochrome P450 11B1, mitochondrial Inhibitor 5-(6-methoxynaph... 7 4
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor 5-hexy... 4 5
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(1,5-naph... 4 20
Cannabinoid receptor 1 Ligand 1-(2-morpholinoethyl)-1h-indol-3... 8 46
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 3 1
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 5 0
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 6 4
Histamine H3 receptor and Sodium-dependent serotonin transport... 3 2
Histamine H3 receptor and Sodium-dependent serotonin transport... 2 0
Glucocorticoid receptor ligand SureCN3894124 family 3 0
Bifunctional epoxide hydrolase 2 and Voltage-dependent L-type ... 2 1
Lanosterol synthase inhibitor AGN-PC-07BZTX family 2 0
Squalene monooxygenase inhibitor N-[2-[3-[[[(E)-6,6-dimethylhe... 1 0
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00419461 CHEMBL236783 Bioactive SureCN3768744
CFAMM00419465 CHEMBL400831 Bioactive SureCN3771369
CFAMM00419463 CHEMBL236784 Bioactive SureCN3766907

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27046 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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