CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1300
Family Name Integrin beta-3 and Integrin alpha-V inhibitor 2-(2,3-dihydro-1-benzofuran-6-yl)-3-[5-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)pentanoylamino]propanoic acid family
No. of Seeds 13 No. of Other Members 1
Family Centroid CFAMM00321707 Functional Category Bioactive
Superfamily Integrin beta-3 and Integrin alpha-V Binder Superfamily 4
Class Class 851

Cousin Family NamesSeedsMembers
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Endothelin-1 receptor and Endothelin B receptor ligand (5S,6R,... 23 8
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(4-ethox... 4 5
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(1,3-ben... 6 5
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN2059024 f... 6 3
Integrin beta-3 and Integrin alpha-V inhibitor (3S,7S)-7-hydro... 5 1
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-3-[5-methy... 4 5
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(1,3-ben... 8 3
Integrin beta-3 and Integrin alpha-V inhibitor SureCN8335217 f... 2 1
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-2-[(2,6-di... 14 8
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-2-[(4-fluo... 7 1
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-2-[(3,5-di... 1 0
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-03OERH f... 1 0
Peroxisome proliferator-activated receptor gamma and Cytochrom... 1 1
Integrin beta-3 and Integrin alpha-V inhibitor SureCN244675 fa... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00321708 CHEMBL83045 Bioactive SureCN6421192
CFAMM00321714 CHEMBL115855 Bioactive AGN-PC-0750BZ
CFAMM00321707 CHEMBL331132 Bioactive 2-(2,3-dihydro-1-benzofuran-6-yl)-3-[5-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)pentanoylamino]propanoic acid
CFAMM00321713 CHEMBL116273 Bioactive SureCN7514286
CFAMM00321706 CHEMBL119710 Bioactive 2-(2,3-dihydro-1-benzofuran-6-yl)-3-[methyl-[3-(1,2,3,4,6,7,8,9-octahydrobenzo[b][1,8]naphthyridin-8-yl)propanoyl]amino]propanoic acid
CFAMM00321712 CHEMBL116142 Bioactive AGN-PC-0750BM
CFAMM00321705 CHEMBL142194 Bioactive SureCN6360770
CFAMM00321711 CHEMBL115976 Bioactive AGN-PC-03PSW7
CFAMM00321704 CHEMBL135757 Bioactive SureCN3893571
CFAMM00321710 CHEMBL330956 Bioactive AGN-PC-0750BX
CFAMM00321703 CHEMBL54063 Bioactive (3S)-3-[[2-[6-cyclopropyl-2-oxo-3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-ylmethylamino)pyridin-1-yl]acetyl]amino]-3-(2,3-dihydro-1-benzofuran-6-yl)propanoic acid
CFAMM00321709 CHEMBL53003 Bioactive (3S)-3-[[2-[3-chloro-2-cyclopropyl-6-oxo-5-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-ylmethylamino)pyrazin-1-yl]acetyl]amino]-3-(2,3-dihydro-1-benzofuran-6-yl)propanoic acid
CFAMM00321702 CHEMBL338725 Bioactive SureCN3886509

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27281 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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