CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13003
Family Name C-C chemokine receptor type 2 ligand SureCN5946889 family
No. of Seeds 2 No. of Other Members 6
Family Centroid CFAMM00419618 Functional Category Bioactive
Superfamily C-C chemokine receptor type 2 and C-C chemokine receptor type 3 Binder Superfamily
Class Class 3182

Cousin Family NamesSeedsMembers
D(2) dopamine receptor Ligand Sertindole Family 3 173
Indoleamine 2,3-dioxygenase 1 Inhibitor L-tryptophan Family 8 328
Glycogen phosphorylase, muscle form Inhibitor PSN357 Family 3 253
Substance-P receptor Ligand GSK424887 Family 8 184
ABC294640 family 5 75
Gastrin/cholecystokinin type B receptor Ligand PD136450 Family 53 117
Lethal factor Inhibitor GM6001 Family 50 435
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... 12 70
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 6 48
Substance-K receptor and Substance-P receptor Ligand L-732138 ... 8 147
Integrin beta-3 Inhibitor Elarofiban Family 28 45
Acetylcholinesterase and Cholinesterase Inhibitor Lipocrine Fa... 18 36
Angiotensin-converting enzyme and Endothelin-converting enzyme... 2 10
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
Endothelin B receptor Ligand IRL-2500 Family 34 87
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14
RAC-alpha serine/threonine-protein kinase and Cyclin-dependent... 3 7
Vasopressin V2 receptor and Vasopressin V1a receptor ligand [2... 2 5
Melanin-concentrating hormone receptor 1 ligand AGN-PC-072CVE ... 4 4
Somatostatin receptor type 2 ligand tert-butyl (2S)-6-amino-2-... 2 15
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 3 0
cGMP-specific 3',5'-cyclic phosphodiesterase and Dual 3',5'-cy... 4 129
Acetylcholinesterase inhibitor CHEMBL1651131 family 6 9
Ceramide glucosyltransferase inhibitor AGN-PC-07YS0C family 4 3
Substance-P receptor ligand N-[(2S)-5-[3,5-bis(trifluoromethyl... 4 6
Substance-P receptor and Neuromedin-K receptor ligand SureCN88... 4 14
C-C chemokine receptor type 3 and Probable C-C chemokine recep... 2 4
Histone deacetylase and Histone deacetylase 3 inhibitor (3S,6R... 2 2
Renin and Potassium voltage-gated channel subfamily H member 2... 9 2
CGMP-dependent protein kinase inhibitor AGN-PC-075XII family 25 7
CGMP-dependent protein kinase inhibitor AGN-PC-075XJ0 family 9 1
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-009GH... 8 10
Substance-P receptor ligand [3,5-bis(trifluoromethyl)phenyl]-[... 17 1
Coagulation factor X inhibitor 3-chloro-N-[(1S,2S)-2-[[4-(2-ox... 22 3
Gonadotropin-releasing hormone receptor ligand 1-adamantyl-[2-... 3 1
C-C chemokine receptor type 2 ligand 2-[4-(5-amino-1H-indol-3-... 3 2
Seprase and Prolyl endopeptidase inhibitor 7-chloro-N-[2-[(2S)... 3 3
C-C chemokine receptor type 2 ligand SureCN5947024 family 11 0
CGMP-dependent protein kinase inhibitor methyl 2-[[4-[5-(4-flu... 6 1
C-C chemokine receptor type 2 ligand (E)-3-(3,4-dichlorophenyl... 3 2
Gastrin/cholecystokinin type B receptor ligand (2R)-2-[[5-(8-a... 2 3
Bombesin receptor subtype-3 ligand SureCN13887096 family 3 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 2
Neuromedin-B receptor and Gastrin-releasing peptide receptor l... 2 0
KiSS-1 receptor ligand SureCN5132924 family 2 4
C-C chemokine receptor type 2 ligand 3-[1-[1-[1-[(3,4-dichloro... 1 1
Integrin beta-2 and Intercellular adhesion molecule 1 inhibito... 3 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00419618 CHEMBL236930 Bioactive SureCN5946889
CFAMM00419623 CHEMBL399616 Bioactive SureCN5946960

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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