CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13012
Family Name Histamine H3 receptor ligand 4-[4-[4-(piperidin-1-ylmethyl)phenyl]but-3-ynyl]morpholine family
No. of Seeds 3 No. of Other Members 5
Family Centroid CFAMM00419651 Functional Category Bioactive with Natural Product
Superfamily Potassium voltage-gated channel subfamily H member 2 Ligand [1-(4-p-tolyl-butyl)-piperidin-4-yl]-methanol Superfamily
Class Class 2632

Cousin Family NamesSeedsMembers
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Dermatan family 1 11
Histamine H3 receptor and Potassium voltage-gated channel subf... 2 2
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 1 1
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 3 12


External ID

Functional Category

Molecule Name

CFAMM00419651 CHEMBL572388 Bioactive 4-[4-[4-(piperidin-1-ylmethyl)phenyl]but-3-ynyl]morpholine
CFAMM00419649 CHEMBL573090 Bioactive 4-[[4-(4-piperidin-1-ylbut-1-ynyl)phenyl]methyl]morpholine
CFAMM00419655 CHEMBL237087 Bioactive 544707-19-9

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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