CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13016
Family Name Gonadotropin-releasing hormone receptor ligand (3S)-3-[[(2R)-2-[[(2R)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(4S,7R,10R)-2-[(2S)-2-[[(2R)-1-amino-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]-7-[3-(diaminomethylideneamino)propyl]-14,14-dimethyl-4-(2-methylpropyl)-3,6,9,13-tetraoxo-1-oxa-5,8-diazacyclotetradec-10-yl]amino]-4-oxobutanoic acid family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00419673 Functional Category Bioactive
Superfamily E3 ubiquitin-protein ligase Mdm2 and Gonadotropin-releasing hormone receptor Binder Superfamily
Class Class 546

Cousin Family NamesSeedsMembers
HIV protease Inhibitor Indinavir Family 36 211
Gastrin/cholecystokinin type B receptor ligand peptide Pentaga... 26 1171
Somatostatin receptor type 2 ligand octapeptide Octreotide Family 27 172
Bacterial outer membrane Inhibitor Daptomycin Family 6 50
Substance-P receptor Ligand GSK424887 Family 8 184
Growth hormone receptor Ligand EP-51216 Family 34 390
Gastrin/cholecystokinin type B receptor Ligand PD136450 Family 53 117
Substance-K receptor and Substance-P receptor Ligand L-732138 ... 8 147
Delta-type opioid receptor and Gastrin/cholecystokinin type B ... 19 0
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[n... 12 10
Endothelin B receptor Ligand IRL-2500 Family 34 87
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 17 28
Somatostatin receptor type 2 ligand tert-butyl (2S)-6-amino-2-... 1 2
Gonadotropin-releasing hormone receptor ligand (3S)-3-[[(2S)-2... 5 0
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00419673 CHEMBL2371498 Bioactive (3S)-3-[[(2R)-2-[[(2R)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(4S,7R,10R)-2-[(2S)-2-[[(2R)-1-amino-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]-7-[3-(diaminomethylideneamino)propyl]-14,14-dimethyl-4-(2-methylpropyl)-3,6,9,13-tetraoxo-1-oxa-5,8-diazacyclotetradec-10-yl]amino]-4-oxobutanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27257 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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