CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13023
Family Name Caspase-9 and Caspase-8 inhibitor 4-fluoro-2-[[2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]benzoyl]amino]-3-oxobutanoic acid family
No. of Seeds 1 No. of Other Members 11
Family Centroid CFAMM00419722 Functional Category Bioactive with Natural Product
Superfamily Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Inhibitor AZD6482 Superfamily
Class Class 257

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Benazepril Family 7 123
Prostaglandin G/H synthase 2 Inhibitor Mefenamic Acid Family 7 137
Cyclophilin receptor and Cyclosporine receptor Ligand D-43787 ... 2 13
Tyrosine-protein phosphatase non-receptor type 1 Ligand 2-(oxa... 3 11
Cathepsin B and Cathepsin L1 Inhibitor MDL-2170 Family 17 24
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Pol polyprotein inhibitor benzyl N-[(2S,3R)-1-[[(2S,3R,4R)-4-(... 5 26
Cathepsin S inhibitor ethyl 2-[[3-[[(2S)-3-cyclohexyl-2-[(3-me... 3 2
Cathepsin S inhibitor methyl 2-amino-4-[[(2S)-3-cyclohexyl-1-[... 2 3
Angiotensin-converting enzyme inhibitor (2R)-1-[4-carboxy-4-(p... 3 3
Cathepsin B and Calpain-1 catalytic subunit inhibitor AGN-PC-0... 2 0
Cathepsin L1 and Cathepsin K inhibitor benzyl N-[(2S)-4-methyl... 8 22
Neuropeptide Y receptor type 5 ligand SureCN3382773 family 1 13
Pol polyprotein inhibitor 2,5-bis[(2-{[(benzyloxy)carbonyl]ami... 2 3
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 2 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [(3Z,... 1 0
5-hydroxytryptamine receptor 6 ligand AGN-PC-00ADLV family 1 0
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-2-[(4-meth... 2 1
NP Methyl 2-((3s,3a'r,8a's,8b's)-5-ethyl-1',2,3'-trioxo-3',3a'... 7 0
Putative NP ZINC04043929 Family 4 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00419722 CHEMBL237310 Bioactive 4-fluoro-2-[[2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]benzoyl]amino]-3-oxobutanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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