CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13042
Family Name Translocator protein inhibitor AGN-PC-07BUUF family
No. of Seeds 11 No. of Other Members 2
Family Centroid CFAMM00419948 Functional Category Bioactive
Superfamily Translocator protein and Beta-lactamase Binder Superfamily
Class Class 958

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A Ligand Melatonin Family 20 988
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
Cyclooxygenase Inhibitor Indomethacin Family 6 271
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Prostaglandin G/H synthase 2 Inhibitor L-761000 Family 8 44
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 3 16
Glycogen synthase kinase-3 beta and Protein kinase C alpha typ... 2 30
Histamine H3 receptor and Cytochrome P450 2D6 ligand AGN-PC-00... 18 32
Histamine H3 receptor ligand AGN-PC-00BG7Z family 11 49
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 15
Translocator protein inhibitor (4S)-N,N-diethyl-9-(2-fluoranyl... 9 10
Histone deacetylase 6 and Histone deacetylase 1 inhibitor N-hy... 3 2
Translocator protein inhibitor N,N-diethyl-11-(2-fluoroethyl)-... 2 1
Estrogen receptor and Estrogen receptor beta ligand N-[(2R)-4-... 7 11


External ID

Functional Category

Molecule Name

CFAMM00419952 CHEMBL2377342 Bioactive N,N-diethyl-11-(2-fluoroethyl)-1-methoxy-6H-thiochromeno[4,3-b]indole-6-carboxamide
CFAMM00419945 CHEMBL2377357 Bioactive N,N-diethyl-3-(2-fluoroethoxy)-11-methyl-6H-thiochromeno[4,3-b]indole-6-carboxamide
CFAMM00419951 CHEMBL2377341 Bioactive AGN-PC-07BUYY
CFAMM00419943 CHEMBL2377353 Bioactive AGN-PC-07BUUH
CFAMM00419950 CHEMBL2377340 Bioactive N,N-diethyl-11-(2-fluoroethyl)-2-methoxy-6H-thiochromeno[4,3-b]indole-6-carboxamide
CFAMM00419956 CHEMBL2375379 Bioactive AGN-PC-07BUUG
CFAMM00419949 CHEMBL2377344 Bioactive N,N-diethyl-11-(2-fluoroethyl)-8-(trifluoromethoxy)-6H-thiochromeno[4,3-b]indole-6-carboxamide
CFAMM00419955 CHEMBL2377338 Bioactive N,N-diethyl-11-(2-fluoroethyl)-4-methoxy-6H-thiochromeno[4,3-b]indole-6-carboxamide
CFAMM00419948 CHEMBL2377222 Bioactive AGN-PC-07BUUF
CFAMM00419947 CHEMBL2377339 Bioactive N,N-diethyl-11-(2-fluoroethyl)-3-methoxy-6H-thiochromeno[4,3-b]indole-6-carboxamide
CFAMM00419946 CHEMBL2377354 Bioactive AGN-PC-07BUYZ

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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