CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13057
Family Name Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase inhibitor N-(2,4-difluorophenyl)-3-ethyl-3-methyl-2,5-dioxo-1,4-dihydro-1,4-benzodiazepine-7-sulfonamide family
No. of Seeds 5 No. of Other Members 10
Family Centroid CFAMM00420028 Functional Category Bioactive
Superfamily Carbonic anhydrase 2 and Carbonic anhydrase 7 Binder Superfamily
Class Class 3739

Cousin Family NamesSeedsMembers
Caspase-3 Inhibitor 5-(pyrrolidin-1-ylsulfonyl)indoline-2,3-di... 5 35
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor N-(4-s... 12 92
Potassium voltage-gated channel subfamily A member 5 Ligand N-... 8 32
C-C chemokine receptor type 8 Ligand N-(4-phenylsulfamoyl-naph... 4 62
72 kDa type IV collagenase and Collagenase 3 inhibitor SureCN7... 1 8
D(2) dopamine receptor and D(3) dopamine receptor ligand 1,1-d... 2 7
Cannabinoid receptor 2 ligand 4-methyl-3-piperidin-1-ylsulfony... 2 0
Inosine-5'-monophosphate dehydrogenase 2 inhibitor SureCN32339... 2 2
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 1 0
B1 bradykinin receptor and Potassium voltage-gated channel sub... 1 1
B1 bradykinin receptor ligand AGN-PC-04TG1P family 4 1
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor KB-74... 2 0
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor 1,2,3,... 1 0


External ID

Functional Category

Molecule Name

CFAMM00420030 CHEMBL2376325 Bioactive N-(4-chlorophenyl)-3-ethyl-3-methyl-2,5-dioxo-1,4-dihydro-1,4-benzodiazepine-7-sulfonamide
CFAMM00420038 CHEMBL2376316 Bioactive N-(2,4-difluorophenyl)-3,3-diethyl-5-oxo-2,4-dihydro-1H-1,4-benzodiazepine-7-sulfonamide
CFAMM00420028 CHEMBL2376302 Bioactive N-(2,4-difluorophenyl)-3-ethyl-3-methyl-2,5-dioxo-1,4-dihydro-1,4-benzodiazepine-7-sulfonamide
CFAMM00420027 CHEMBL2376303 Bioactive (3S)-N-(2,4-difluorophenyl)-3-ethyl-3-methyl-2,5-dioxo-1,4-dihydro-1,4-benzodiazepine-7-sulfonamide
CFAMM00420034 CHEMBL2376310 Bioactive N-(2,4-difluorophenyl)-3,3-diethyl-2,5-dioxo-1,4-dihydro-1,4-benzodiazepine-7-sulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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