CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1306
Family Name Sodium-dependent serotonin transporter and D(2) dopamine receptor ligand SureCN6816613 family
No. of Seeds 13 No. of Other Members 2
Family Centroid CFAMM00313479 Functional Category Bioactive
Superfamily Melanin-concentrating hormone receptor 1 and Sodium-dependent serotonin transporter Binder Superfamily
Class Class 3193

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
5-hydroxytryptamine receptor 3A Ligand Dolasetron Family 12 171
Histone deacetylase 1 Inhibitor MS-275 Family 4 41
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
Substance-K receptor and Substance-P receptor Ligand L-732138 ... 8 147
Vascular endothelial growth factor receptor 2 Ligand Isoindoli... 11 36
DNA-dependent protein kinase catalytic subunit Inhibitor 8-(1h... 3 85
Tyrosine-protein phosphatase non-receptor type 1 Ligand Cauler... 2 8
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-366... 5 75
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Kinesin-like protein KIF11 Inhibitor Methyl 7-tert-butyl-9h-ca... 2 9
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 24 64
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 12 72
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
5-hydroxytryptamine receptor 3A Ligand 3alpha-(1'-methyl-2'-in... 2 17
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 10 4
Renin inhibitor [(2S,4S,5S,7R)-4-amino-8-(butylamino)-5-hydrox... 3 1
Pol polyprotein and Protease inhibitor Palinavir family 1 0
Retinoic acid receptor alpha and Retinoic acid receptor beta l... 1 2
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 5 2
Survival motor neuron protein and Nonstructural protein 1 inhi... 1 18
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 16
Cannabinoid receptor 2 ligand [(4R,4aS,8aR)-4-hydroxy-4-phenyl... 2 41
Dipeptidyl peptidase 4 inhibitor AGN-PC-09QM95 family 1 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [(4S,... 5 2
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 5 2
Renin and Potassium voltage-gated channel subfamily H member 2... 13 11
Muscarinic acetylcholine receptor M3 ligand [(3R)-1-[2-(1H-ind... 1 0
Egl nine homolog 1 inhibitor 2-[5-methyl-6-[[1-oxo-2-(4-phenyl... 4 3
B1 bradykinin receptor ligand methyl 2-[4-[(1R)-1-[[3-[(2-cyan... 8 7
Rho-associated protein kinase 2 inhibitor 2-hydroxyethyl 3-[2-... 2 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand SureC... 1 3
Cyclin-dependent kinase 2 and Vascular endothelial growth fact... 1 1
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 0
Gonadotropin-releasing hormone receptor ligand methyl 4-[2-[[(... 2 1
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 2 0
Beta-3 adrenergic receptor ligand SureCN5704018 family 4 1
TGF-beta receptor type-1 ligand Methyl 4-(4-(3-(pyridin-2-yl)-... 1 2
Serine/threonine-protein kinase pim-3 inhibitor methyl 6-amino... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00321761 CHEMBL310744 Bioactive 1-[2-[4-(6-fluoro-1H-indol-3-yl)piperazin-1-yl]ethyl]-3,4-dihydro-1H-isochromene-6-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26413 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543