CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13060
Family Name Cholinesterase and Acetylcholinesterase inhibitor 6-[4-[2-fluoro-4-[1-oxo-1-[6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexylamino]propan-2-yl]phenyl]phenoxy]hexyl nitrate family
No. of Seeds 17 No. of Other Members 0
Family Centroid CFAMM00182887 Functional Category Bioactive
Superfamily Disintegrin and metalloproteinase domain-containing protein 17 Binder Superfamily 9
Class Class 1076

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Dibucaine F... 2 136
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Neuromedin-K receptor Ligand 3-methoxy-n',2-diphenylquinoline-... 14 33
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
Neuromedin-K receptor and Substance-K receptor ligand 2-[2-phe... 2 2
Disintegrin and metalloproteinase domain-containing protein 17... 2 8
Acetylcholinesterase and Muscarinic acetylcholine receptor M2 ... 2 7
Cysteinyl leukotriene receptor 1 ligand 4-[(2S)-2-[[7-(quinoli... 6 15
Somatostatin receptor type 5 and Somatostatin receptor type 1 ... 2 8
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 6
Cysteinyl leukotriene receptor 1 ligand SureCN7808360 family 4 11
Cysteinyl leukotriene receptor 1 ligand AGN-PC-075KCE family 5 33
B2 bradykinin receptor ligand SureCN6640854 family 7 4
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 3 21
Butyrylcholinesterase and Acetylcholinesterase inhibitor AGN-P... 9 24
Prostaglandin D2 receptor 2 ligand SureCN137822 family 3 0
Cholinesterase and Acetylcholinesterase inhibitor 4-oxo-N-[9-(... 11 13
Disintegrin and metalloproteinase domain-containing protein 17... 13 3
Substance-P receptor ligand 1-[4-(2-methoxyphenyl)piperazin-1-... 11 12
Disintegrin and metalloproteinase domain-containing protein 17... 16 2
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 42 20
Acetylcholinesterase and Butyrylcholinesterase inhibitor (E)-3... 4 5
Cholinesterase and Acetylcholinesterase inhibitor 6-[2-methoxy... 12 6
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 19 11
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL4... 6 2
Prothrombin inhibitor AGN-PC-074I2Z family 2 1
Proteinase-activated receptor 1 ligand 2-[2-[(E)-2-[(3R,3aS,4S... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00420045 CHEMBL2380603 Bioactive 6-[4-[2-fluoro-4-[1-oxo-1-[2-(1,2,3,4-tetrahydroacridin-9-ylamino)ethylamino]propan-2-yl]phenyl]phenoxy]hexyl nitrate
CFAMM00420044 CHEMBL2376474 Bioactive 2-[4-[2-fluoro-4-[1-oxo-1-[6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexylamino]propan-2-yl]phenyl]phenoxy]ethyl nitrate
CFAMM00420043 CHEMBL2380611 Bioactive 6-[4-[2-fluoro-4-[1-oxo-1-[4-(1,2,3,4-tetrahydroacridin-9-ylamino)butylamino]propan-2-yl]phenyl]phenoxy]hexyl nitrate
CFAMM00420046 CHEMBL2380607 Bioactive 6-[4-[2-fluoro-4-[1-oxo-1-[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propylamino]propan-2-yl]phenyl]phenoxy]hexyl nitrate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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