CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13062
Family Name 5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine receptor 1B ligand 2-methyl-5-nitro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00420052 Functional Category Bioactive
Superfamily D(2) dopamine receptor and 5-hydroxytryptamine receptor 6 Binder Superfamily
Class Class 1410

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and D(1A) dopamine receptor ligand ergo... 12 720
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 4 171
Acetylcholinesterase Inhibitor Tacrine Family 12 515
Histamine H1 receptor Ligand Triprolidine Family 19 316
Glucagon receptor Ligand Dwlip-gcgrrx Family 5 26
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
D(1B) dopamine receptor Ligand LE-300 Family 65 452
Histone deacetylase 1 Inhibitor Panobinostat Family 5 93
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 6 17
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 6 48
Potassium voltage-gated channel subfamily H member 2 Ligand 5-... 5 14
5-hydroxytryptamine receptor 2A Ligand 8-chloro-1,2,3,4-tetrah... 5 4
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 8-(3... 4 22
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 6 24
Cholinesterase Inhibitor 9-[9-(beta-carboline-9-yl)nonyl]-beta... 7 7
Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... 94 23
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 6 10
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 1 1
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 1 3
5-hydroxytryptamine receptor 2A and Amine oxidase [flavin-cont... 10 18
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 3-chlo... 3 2
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 12 72
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 1 0
Histone deacetylase Inhibitor ST-5732 Family 8 6
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 62 27
D(2) dopamine receptor and 5-hydroxytryptamine receptor 2C lig... 2 3
D(4) dopamine receptor and D(1A) dopamine receptor ligand 2-[[... 5 4
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 1 0
5-hydroxytryptamine receptor 6 ligand 2-methyl-5-methylsulfany... 1 1
Gamma-aminobutyric acid receptor subunit beta-3 and Gamma-amin... 2 5
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 1
Potassium voltage-gated channel subfamily A member 5 and Volta... 2 4
Lysine-specific demethylase 4E and Lethal(3)malignant brain tu... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00420053 CHEMBL78766 Bioactive AGN-PC-000LVD
CFAMM00420052 CHEMBL2376487 Bioactive 2-methyl-5-nitro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27397 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543