CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1308
Family Name Plasminogen and Plasma kallikrein inhibitor CHEMBL2016864 family
No. of Seeds 9 No. of Other Members 16
Family Centroid CFAMM00190257 Functional Category Bioactive
Superfamily Prothrombin and Coagulation factor X Binder Superfamily 3
Class Class 1271

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor Ligand Felypressin Family 12 820
Prothrombin Inhibitor Ximelagatran Family 5 48
Neuropeptide Y receptor type 1 Ligand BIBO3304 Family 4 69
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
Suppressor of tumorigenicity 14 protein and Prothrombin Inhibi... 4 126
Prothrombin Inhibitor LB30812 Family 12 36
Prothrombin Inhibitor D-leucyl-n-(4-carbamimidoylbenzyl)-l-pro... 13 44
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Tic... 11 31
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Suppressor of tumorigenicity 14 protein Inhibitor 3-tapap Family 15 39
Substance-P receptor Ligand [sar9,met(o2)11]-sp Family 34 9
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Trypsin Inhibitor Benzamidrazone Analogue Family 16 6
Coagulation factor X inhibitor (6S,8aS)-2-benzhydrylsulfonyl-N... 5 5
Prothrombin and Cationic trypsin inhibitor (2S)-1-[(2R)-2-anil... 1 2
Prothrombin and Suppressor of tumorigenicity 14 protein inhibi... 5 8
Prothrombin inhibitor SureCN7341151 family 6 7
Prothrombin inhibitor (2S)-N-[4-(2-amino-2-iminoethyl)cyclohex... 2 0
Trypsin-1 and Urokinase-type plasminogen activator inhibitor (... 3 9
Coagulation factor X inhibitor (6S,8aS)-N-[(1-carbamimidoylpip... 6 0
Prothrombin and Coagulation factor X inhibitor tert-butyl (4R)... 1 0
Prothrombin and Transmembrane protease serine 11D inhibitor be... 1 4
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 3 0
Prothrombin inhibitor 2-[3-(benzylsulfonylamino)-6-methyl-2-ox... 2 3
Suppressor of tumorigenicity 14 protein and Plasminogen inhibi... 10 15
B1 bradykinin receptor and B2 bradykinin receptor ligand SureC... 3 0
Plasminogen and Trypsin-1 inhibitor CHEMBL2315239 family 13 1
Prothrombin inhibitor (2S,3aS,7aS)-N-[(4-carbamimidoylphenyl)m... 8 7
Prothrombin and Cationic trypsin inhibitor (2S)-N-[[4-[(Z)-C-a... 6 3
Coagulation factor X inhibitor ethyl 2-[[(3S)-3-[[2-[[(2R)-2-(... 4 0
Suppressor of tumorigenicity 14 protein and Prothrombin inhibi... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00322055 CHEMBL1159686 Bioactive (2S)-1-[(2R)-2-(benzylsulfonylamino)-3,3-diphenylpropanoyl]-N-[(4-carbamimidoylphenyl)methyl]pyrrolidine-2-carboxamide;2,2,2-trifluoroacetic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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