CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1309
Family Name Prothrombin and Cationic trypsin inhibitor (2S)-1-[(2R)-2-anilino-3,3-diphenylpropanoyl]-N-[(4-carbamimidoylphenyl)methyl]pyrrolidine-2-carboxamide;2,2,2-trifluoroacetic acid family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00322064 Functional Category Bioactive
Superfamily Furin and Trypsin-1 Binder Superfamily
Class Class 2794

Cousin Family NamesSeedsMembers
Prothrombin Inhibitor Ximelagatran Family 5 48
Motilin receptor Ligand GSK962040 Family 30 457
Neuropeptide Y receptor type 1 Ligand BIBO3304 Family 4 69
Prothrombin Inhibitor LB30812 Family 12 36
Prothrombin Inhibitor D-leucyl-n-(4-carbamimidoylbenzyl)-l-pro... 13 44
Urokinase-type plasminogen activator Inhibitor 6-(n-phenylcarb... 2 11
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Tic... 11 31
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 1 1
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Prothrombin and Plasminogen inhibitor [(1R)-5-amino-1-[[2-[N-(... 1 0
Substance-P receptor ligand (2S)-2-N-[(2S)-1-[benzyl(methyl)am... 6 3
Coagulation factor X inhibitor (6S,8aS)-2-benzhydrylsulfonyl-N... 5 5
72 kDa type IV collagenase and Stromelysin-1 inhibitor [(2S)-2... 9 6
Plasminogen and Plasma kallikrein inhibitor CHEMBL2016864 family 9 16
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7345980... 4 6
Coagulation factor X and Trypsin-1 inhibitor 3-carbamimidoyl-N... 1 1
Baculoviral IAP repeat-containing protein 2 and E3 ubiquitin-p... 2 1
Kappa-type opioid receptor ligand (2R)-6-amino-2-[[(2R)-2-[[(2... 2 1
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 11 9
Plasminogen and Trypsin-1 inhibitor CHEMBL2315239 family 13 1
Prothrombin inhibitor (2S,3aS,7aS)-N-[(4-carbamimidoylphenyl)m... 8 7
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 11 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00322064 CHEMBL1159689 Bioactive (2S)-1-[(2R)-2-anilino-3,3-diphenylpropanoyl]-N-[(4-carbamimidoylphenyl)methyl]pyrrolidine-2-carboxamide;2,2,2-trifluoroacetic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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