CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13100
Family Name Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor N-(5-hydroxy-2-adamantyl)-4-[5-(4-methoxyphenyl)pyrimidin-2-yl]-2,3-dihydroquinoxaline-1-carboxamide family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00420445 Functional Category Bioactive
Superfamily Histamine H3 receptor and Cytochrome P450 3A4 Binder Superfamily
Class Class 666

Cousin Family NamesSeedsMembers
SB1518 family 7 103
Platelet-derived growth factor receptor alpha and Fibroblast g... 3 47
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 3
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 0
Melanin-concentrating hormone receptor 1 ligand SureCN3334861 ... 1 3
Cholecystokinin receptor type A ligand AGN-PC-0A9ULH family 8 8
Histamine H1 receptor and Histamine H4 receptor ligand 1H-benz... 2 7
Dihydrofolate reductase inhibitor AC1LAPW3 family 3 0
Calcitonin gene-related peptide type 1 receptor ligand SureCN1... 1 3


External ID

Functional Category

Molecule Name

CFAMM00420445 CHEMBL2380637 Bioactive N-(5-hydroxy-2-adamantyl)-4-[5-(4-methoxyphenyl)pyrimidin-2-yl]-2,3-dihydroquinoxaline-1-carboxamide
CFAMM00420447 CHEMBL2380640 Bioactive [4-[[4-[5-(4-methoxyphenyl)pyrimidin-2-yl]-2,3-dihydroquinoxaline-1-carbonyl]amino]-1-adamantyl] carbamate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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