CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13101
Family Name Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor N-(5-hydroxy-2-adamantyl)-4-[5-(4-methylsulfonylpiperazin-1-yl)pyridin-2-yl]-2,3-dihydroquinoxaline-1-carboxamide family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00420449 Functional Category Bioactive
Superfamily Corticosteroid 11-beta-dehydrogenase isozyme 1 and Lethal factor Binder Superfamily
Class Class 960

Cousin Family NamesSeedsMembers
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 7 6
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 6 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Corticoster... 2 0


External ID

Functional Category

Molecule Name

CFAMM00420450 CHEMBL2380641 Bioactive N-(5-hydroxy-2-adamantyl)-4-[5-(4-methylsulfonylpiperazin-1-yl)pyrimidin-2-yl]-2,3-dihydroquinoxaline-1-carboxamide
CFAMM00420449 CHEMBL2380642 Bioactive N-(5-hydroxy-2-adamantyl)-4-[5-(4-methylsulfonylpiperazin-1-yl)pyridin-2-yl]-2,3-dihydroquinoxaline-1-carboxamide
CFAMM00420448 CHEMBL2380647 Bioactive 4-[5-(4-cyclopropylsulfonylpiperazin-1-yl)pyridin-2-yl]-N-(5-hydroxy-2-adamantyl)-2,3-dihydroquinoxaline-1-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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