CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13104
Family Name Cathepsin S inhibitor (2S,4R)-4-(benzenesulfonyl)-N-[1-(1,3-benzoxazol-2-yl)-1-oxobutan-2-yl]-1-(4-chlorobenzoyl)pyrrolidine-2-carboxamide family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00420456 Functional Category Bioactive
Superfamily Chymase Inhibitor Y-40613 Superfamily
Class Class 828

Cousin Family NamesSeedsMembers
C-C chemokine receptor type 2 and C-C motif chemokine 2 Ligand... 3 52
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Chymase Inhibitor Y-40613 Family 11 56
Neutrophil elastase Inhibitor Cbz-val-pro-val-(2-benzoxazole) ... 32 64
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 1 4
Fatty-acid amide hydrolase 1 Inhibitor 3-(benzo[d]oxazol-2-yl)... 1 6
Neutrophil elastase inhibitor 1-N-[(2S)-1-[(2S)-2-[[(2S)-1-(1,... 7 1
Neutrophil elastase inhibitor methyl 2-[(2S)-3-methyl-2-[[(2S)... 2 0
Pol polyprotein inhibitor (2S)-4-(1,3-benzoxazol-2-ylmethyl)-1... 1 0
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 5 12
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 4 1
Cathepsin S inhibitor (2S,4R)-4-(benzenesulfonyl)-N-[1-(1,3-be... 4 0
Coagulation factor X and Plasma kallikrein inhibitor (2R)-N-[2... 1 0
Neutrophil elastase inhibitor methyl 2-[(2S)-2-[[(2S)-1-[(2S)-... 3 0
Cathepsin S and Cathepsin L1 inhibitor (2S)-2-(1,3-benzoxazol-... 1 9


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00420458 CHEMBL2380726 Bioactive (2S,4R)-4-(benzenesulfonyl)-N-[1-(1,3-benzoxazol-2-yl)-1-oxobutan-2-yl]-1-(4-phenylbenzoyl)pyrrolidine-2-carboxamide
CFAMM00420457 CHEMBL2380725 Bioactive (2S,4R)-4-(benzenesulfonyl)-N-[1-(1,3-benzoxazol-2-yl)-1-oxobutan-2-yl]-1-(3-chlorobenzoyl)pyrrolidine-2-carboxamide
CFAMM00420456 CHEMBL2380724 Bioactive (2S,4R)-4-(benzenesulfonyl)-N-[1-(1,3-benzoxazol-2-yl)-1-oxobutan-2-yl]-1-(4-chlorobenzoyl)pyrrolidine-2-carboxamide
CFAMM00420455 CHEMBL2380727 Bioactive (2S,4R)-1-acetyl-N-[1-(1,3-benzoxazol-2-yl)-1-oxobutan-2-yl]-4-(2-chlorophenyl)sulfonylpyrrolidine-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543