CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13112
Family Name Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 inhibitor 2-(3-chloro-4-fluorophenyl)-3-(4-methylsulfonylphenyl)cyclopent-2-en-1-one family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00420508 Functional Category Bioactive
Superfamily Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 1-(3,4-dichlorophenyl)-2-(phenylsulfonyl)ethanone Superfamily
Class Class 2459

Cousin Family NamesSeedsMembers
Cytochrome P450 11B1, mitochondrial Inhibitor 3-meso2-dde Family 2 14
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 11 80
Presenilin-1 and Presenilin-2 Inhibitor 1-chloro-4-(1-phenyl-c... 5 13
Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 1,1-d... 1 2
Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 1-phe... 6 23
Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 1-(3,... 2 5
Prostaglandin G/H synthase 2 inhibitor SureCN8385166 family 4 2
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 2 0
Prostaglandin G/H synthase 2 inhibitor AGN-PC-075FEE family 4 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00420508 CHEMBL23808 Bioactive 2-(3-chloro-4-fluorophenyl)-3-(4-methylsulfonylphenyl)cyclopent-2-en-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

78410 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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