Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database. Cousin Family Names Seeds Members Alpha adrenergic receptor Ligand Phenoxybenzamine Family 4 63 Substance-P receptor Ligand Ezlopitant Family 10 207 Potassium voltage-gated channel subfamily H member 2 and Sodiu... 33 83 Fibroblast growth factor receptor Ligand SU5403 Family 8 8 Histamine H3 receptor Ligand UCL-2138 Family 23 172 5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 25 50 Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 41 Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28 Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 11 Sodium-dependent serotonin transporter Inhibitor 4-(2-((dimeth... 3 1 Sodium-dependent noradrenaline transporter Inhibitor WAY-25680... 4 6 Histamine H3 receptor ligand cyclohexyl-[4-(3-piperidin-1-ylpr... 4 1 Substance-P receptor ligand (5S,10S)-5-(4-fluorophenyl)-10-(2-... 3 2 Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 6 Sodium-dependent serotonin transporter and Sodium-dependent no... 2 11 Sigma non-opioid intracellular receptor 1 ligand (1R,5S)-9-[(4... 3 2 2-[(1R,4aS,8aS)-4a-hydroxy-1-(4-methoxyphenyl)-2,3,4,5,6,7,8,8... 1 0
CFAM Mol ID
External ID
Functional Category
Molecule Name
CFAM Mol ID
External ID
Functional Category
Molecule Name
CFAMM00420638 CHEMBL523495 Bioactive
(1S,4Z,5S)-4-benzylidene-9-[(2,4-dimethoxyphenyl)methyl]-7-prop-2-enyl-7,9-diazabicyclo[3.2.2]nonane CFAMM00420634 CHEMBL513736 Bioactive
(1R,5S)-7-benzyl-9-[(4-methoxyphenyl)methyl]-7,9-diazabicyclo[3.2.2]nonan-4-one CFAMM00420633 CHEMBL522703 Bioactive
(1R,4Z,5R)-4-benzylidene-9-[(2,4-dimethoxyphenyl)methyl]-7-prop-2-enyl-7,9-diazabicyclo[3.2.2]nonane CFAMM00420637 CHEMBL492736 Bioactive
7-benzyl-9-[(4-methoxyphenyl)methyl]-7,9-diazabicyclo[3.2.2]nonan-4-one CFAMM00420635 CHEMBL471013 Bioactive
(1S,5R)-7-benzyl-9-[(4-methoxyphenyl)methyl]-7,9-diazabicyclo[3.2.2]nonan-4-one CFAMM00420640 ZINC20112750 Natural Product
AC1NU2H3 CFAMM00420630 ZINC20112752 Natural Product
2-(((1R,2R)-1-hydroxy-1-phenylpropan-2-yl)(methyl)amino)-2-(4-methoxyphenyl)acetonitrile
Statistics of CFAM Database
490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
How to cite our database
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering.
Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
Last update by
2014.08.29
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