CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13137
Family Name Sigma non-opioid intracellular receptor 1 ligand (1S,4R,5R)-7-benzyl-9-[(4-methoxyphenyl)methyl]-7,9-diazabicyclo[3.2.2]nonan-4-ol family
No. of Seeds 2 No. of Other Members 7
Family Centroid CFAMM00420636 Functional Category Bioactive with Natural Product
Superfamily Prelamin-A/C and Sigma non-opioid intracellular receptor 1 Binder Superfamily
Class Class 4753

Cousin Family NamesSeedsMembers
Alpha adrenergic receptor Ligand Phenoxybenzamine Family 4 63
Substance-P receptor Ligand Ezlopitant Family 10 207
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 33 83
Fibroblast growth factor receptor Ligand SU5403 Family 8 8
Histamine H3 receptor Ligand UCL-2138 Family 23 172
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 25 50
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 41
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 11
Sodium-dependent serotonin transporter Inhibitor 4-(2-((dimeth... 3 1
Sodium-dependent noradrenaline transporter Inhibitor WAY-25680... 4 6
Histamine H3 receptor ligand cyclohexyl-[4-(3-piperidin-1-ylpr... 4 1
Substance-P receptor ligand (5S,10S)-5-(4-fluorophenyl)-10-(2-... 3 2
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 6
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 11
Sigma non-opioid intracellular receptor 1 ligand (1R,5S)-9-[(4... 3 2
2-[(1R,4aS,8aS)-4a-hydroxy-1-(4-methoxyphenyl)-2,3,4,5,6,7,8,8... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00420636 CHEMBL238176 Bioactive (1S,4R,5R)-7-benzyl-9-[(4-methoxyphenyl)methyl]-7,9-diazabicyclo[3.2.2]nonan-4-ol
CFAMM00420639 CHEMBL391007 Bioactive (1R,4S,5S)-7-benzyl-9-[(4-methoxyphenyl)methyl]-7,9-diazabicyclo[3.2.2]nonan-4-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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