CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13157
Family Name Dipeptidyl peptidase 4 inhibitor 4-[4-[(3S,5S)-5-(1,3-thiazolidine-3-carbonyl)pyrrolidin-3-yl]piperazin-1-yl]benzonitrile family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00420831 Functional Category Bioactive
Superfamily Dipeptidyl peptidase 4 and Androgen receptor Binder Superfamily
Class Class 1613

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Procainamid... 7 291
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 43 161
5-hydroxytryptamine receptor 1A and Sigma non-opioid intracell... 7 28
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
Aromatase Inhibitor 3-(4-amino-phenyl)-1-methyl-pyrrolidine-2,... 4 8
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Leukotriene A-4 hydrolase Inhibitor N5-[4-benzylphenyl]-l-glut... 2 1
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
D(4) dopamine receptor ligand 1-Piperidineacetamide, 4-(2-cyan... 3 7
Dipeptidyl peptidase 4 inhibitor SureCN296150 family 3 8
Dipeptidyl peptidase 4 inhibitor (2S)-1-[(2S,4S)-4-anilinopyrr... 2 13
Baculoviral IAP repeat-containing protein 2 and E3 ubiquitin-p... 2 1
Dipeptidyl peptidase 4 inhibitor SureCN2709139 family 5 7
Oxytocin receptor ligand (2R)-2-[(2R,5R)-5-(2,3-dihydro-1H-ind... 2 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor [(... 2 23
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-(5-bromo-2,3-dihyd... 2 1
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-(5-nitro-2,3-dihyd... 2 6
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(4-chlorophenyl... 3 3
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(4-nitrophenyl)... 3 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (2... 3 0
Dipeptidyl peptidase 4 inhibitor 4-[[(3S,5S)-5-[(2S)-2-cyanopy... 4 12
Dipeptidyl peptidase 4 inhibitor (2S,4S)-1-[2-[[1-[4-cyano-2-(... 2 0
72 kDa type IV collagenase and Disintegrin and metalloproteina... 1 5
Cathepsin K and Cathepsin B inhibitor AGN-PC-076LFZ family 1 0
5-hydroxytryptamine receptor 4 ligand 2-oxo-N-[(1R,5S)-8-(2-pi... 13 5
Voltage-dependent N-type calcium channel subunit alpha-1B liga... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00420831 CHEMBL391578 Bioactive 4-[4-[(3S,5S)-5-(1,3-thiazolidine-3-carbonyl)pyrrolidin-3-yl]piperazin-1-yl]benzonitrile
CFAMM00420830 CHEMBL241245 Bioactive 1,3-thiazolidin-3-yl-[(2S,4S)-4-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]pyrrolidin-2-yl]methanone
CFAMM00420834 CHEMBL238515 Bioactive SureCN2711753

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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