CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1316
Family Name Growth factor receptor-bound protein 2 ligand (3-aminophenyl)methyl N-[(2S)-1-[[1-[[(2S)-1,4-diamino-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-1-oxo-3-(4-phosphonooxyphenyl)propan-2-yl]carbamate family
No. of Seeds 5 No. of Other Members 13
Family Centroid CFAMM00322119 Functional Category Bioactive
Superfamily Signal transducer and Growth factor receptor-bound protein 2 Binder Superfamily
Class Class 3261

Cousin Family NamesSeedsMembers
Proto-oncogene tyrosine-protein kinase Src Inhibitor RU84687 F... 2 14
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 12 46
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 8 4
Pol polyprotein inhibitor benzyl N-[(2S,3R)-1-[[(2S,3R,4R)-4-(... 5 26
Cathepsin L1 and Cathepsin K inhibitor benzyl N-[(2S)-4-methyl... 8 22
Matrilysin and Interstitial collagenase inhibitor [2-[(1,3-dia... 1 0


External ID

Functional Category

Molecule Name

CFAMM00322108 CHEMBL334099 Bioactive AGN-PC-0752TN
CFAMM00322119 CHEMBL77689 Bioactive (3-aminophenyl)methyl N-[(2S)-1-[[1-[[(2S)-1,4-diamino-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-1-oxo-3-(4-phosphonooxyphenyl)propan-2-yl]carbamate
CFAMM00322112 CHEMBL307890 Bioactive 1cj1
CFAMM00322110 CHEMBL1160046 Bioactive (3-aminophenyl)methyl N-[(2S)-1-[[1-[[(6S)-6-carbamoylcyclohex-2-en-1-yl]carbamoyl]cyclohexyl]amino]-1-oxo-3-(4-phosphonooxyphenyl)propan-2-yl]carbamate
CFAMM00322123 CHEMBL49860 Bioactive AGN-PC-073QN2

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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