CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13172
Family Name MAP kinase-activated protein kinase 2 inhibitor 4-[4-oxo-8-piperidin-4-yl-5-[(2-pyrimidin-5-ylphenyl)methyl]-10H-furo[2,3-c][1]benzazepin-2-yl]benzonitrile family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00420893 Functional Category Bioactive
Superfamily Cathepsin K and Neuronal acetylcholine receptor subunit alpha-4 Binder Superfamily
Class Class 918

Cousin Family NamesSeedsMembers
Neuronal acetylcholine receptor subunit alpha-4 Ligand TC-5619... 3 61
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 12 197
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Mitogen-activated protein kinase 14 inhibitor N-(4-aminobutyl)... 1 28
Gonadotropin-releasing hormone receptor ligand AGN-PC-034WF4 f... 8 23
Collagenase 3 inhibitor N-[[3-[5-[[(1R)-1-cyclohexyl-2-(methyl... 6 9
Collagenase 3 inhibitor N-[[3-[5-[[(1R)-1-cyclohexyl-2-(methyl... 4 2
Serine/threonine-protein kinase B-raf inhibitor furan-based co... 6 3
MAP kinase-activated protein kinase 2 inhibitor CHEMBL1938684 ... 5 6
MAP kinase-activated protein kinase 2 inhibitor 5-(4-cyanophen... 3 8
MAP kinase-activated protein kinase 2 inhibitor 4-[5-[4-(4-pip... 1 11
MAP kinase-activated protein kinase 2 inhibitor 4-[5-[[2-(2-me... 3 4
Macrophage colony-stimulating factor 1 receptor ligand 5-cyano... 1 0
Cathepsin K and Cathepsin L1 inhibitor AC1NR9VX family 2 2
MAP kinase-activated protein kinase 2 inhibitor 3-[5-(4-chloro... 6 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00420896 CHEMBL2385550 Bioactive 4-[10,10-difluoro-4-oxo-8-piperidin-4-yl-5-[(2-pyrimidin-5-ylphenyl)methyl]furo[2,3-c][1]benzazepin-2-yl]benzonitrile
CFAMM00420895 CHEMBL2385547 Bioactive 2-(4-chlorophenyl)-8-piperazin-1-yl-5-[(2-pyrimidin-5-ylphenyl)methyl]-10H-furo[2,3-c][1]benzazepin-4-one
CFAMM00420894 CHEMBL2385548 Bioactive 4-[4-oxo-8-piperazin-1-yl-5-[(2-pyrimidin-5-ylphenyl)methyl]-10H-furo[2,3-c][1]benzazepin-2-yl]benzonitrile
CFAMM00420893 CHEMBL2385549 Bioactive 4-[4-oxo-8-piperidin-4-yl-5-[(2-pyrimidin-5-ylphenyl)methyl]-10H-furo[2,3-c][1]benzazepin-2-yl]benzonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27075 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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