CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13174
Family Name Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 inhibitor AGN-PC-077NPP family
No. of Seeds 4 No. of Other Members 4
Family Centroid CFAMM00385653 Functional Category Bioactive
Superfamily Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 Binder Superfamily
Class Class 2498

Cousin Family NamesSeedsMembers
Neuronal acetylcholine receptor subunit alpha-4 Ligand TC-5619... 3 61
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 12 197
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 2-benzyl-6-... 9 80
DNA-dependent protein kinase catalytic subunit Inhibitor 8-(1h... 3 85
Serine/threonine-protein kinase Chk1 Inhibitor A-432411 Family 4 70
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 3-(furan-3-... 3 44
Glycogen synthase kinase-3 beta and Protein kinase C alpha typ... 2 30
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 11
Glycogen synthase kinase-3 beta and Protein kinase C alpha typ... 1 18
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 11 391
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 8 12
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 3 3
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 11 11
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 7 1
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 2 0
Translocator protein inhibitor (4S)-N,N-diethyl-9-(2-fluoranyl... 9 10
Serine/threonine-protein kinase pim-2 and cGMP-dependent prote... 8 1
Vascular endothelial growth factor receptor 2 and Vascular end... 2 52
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 42 20
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-(1-... 3 2
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 159
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 1 0
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 1 0
Substance-P receptor ligand SureCN2139814 family 7 7
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 5 0
Glycogen synthase kinase-3 beta inhibitor bip-135 family 3 1
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 6 1
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 0
Bombesin receptor subtype-3 ligand 2-[[(E)-furan-2-ylmethylide... 2 4
Collagenase 3 inhibitor SureCN1316041 family 4 3
Sodium-dependent serotonin transporter inhibitor SureCN5477150... 4 1
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00420903 CHEMBL522590 Bioactive AGN-PC-077NQO
CFAMM00420902 CHEMBL489210 Bioactive AGN-PC-04VCI4
CFAMM00420906 CHEMBL2386096 Bioactive 3-(1-benzofuran-3-yl)-4-[5-fluoro-1-(2-hydroxyethyl)indol-3-yl]pyrrole-2,5-dione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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