CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13176
Family Name Glycogen synthase kinase-3 beta inhibitor 3-imidazo[1,2-a]pyridin-3-yl-4-(5-methyl-[1,3]dioxolo[4,5-f]indol-7-yl)pyrrole-2,5-dione family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00420909 Functional Category Bioactive
Superfamily DNA topoisomerase 1 and Thyroid hormone receptor beta Binder Superfamily
Class Class 2504

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
TGF-beta receptor type-1 Ligand SB-431542 Family 2 42
Reverse transcriptase Inhibitor Atevirdine Family 4 55
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 39 10
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL2... 3 8
Rho-associated protein kinase 1 inhibitor SureCN4007647 family 8 4
Nitric oxide synthase, inducible inhibitor N-(1,3-benzodioxol-... 11 1
Mast/stem cell growth factor receptor Kit and Serine/threonine... 11 29
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 0
Insulin-like growth factor 1 receptor ligand SureCN311483 family 3 0
Dihydrofolate reductase inhibitor AGN-PC-073PP8 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00420909 CHEMBL2386112 Bioactive 3-imidazo[1,2-a]pyridin-3-yl-4-(5-methyl-[1,3]dioxolo[4,5-f]indol-7-yl)pyrrole-2,5-dione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27669 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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