CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13177
Family Name Glycogen synthase kinase-3 beta inhibitor 3-(5-bromo-1-methylindol-3-yl)-4-imidazo[1,2-a]pyridin-3-ylpyrrole-2,5-dione family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00420911 Functional Category Bioactive
Superfamily Vascular endothelial growth factor receptor 2 Ligand XL999 Superfamily
Class Class 1053

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
5-hydroxytryptamine receptor Ligand Ramosetron Family 10 219
Hepatocyte growth factor receptor Ligand Arq 197 Family 10 400
Glycogen synthase kinase-3 beta and Protein kinase C beta type... 5 53
Protein kinase C alpha type and Protein kinase C beta type Inh... 16 86
Histone deacetylase Inhibitor JNJ-26481585 Family 2 5
Platelet activating factor, putative Inhibitor ABT-491 Family 22 62
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 0
Glycogen synthase kinase-3 beta inhibitor AGN-PC-07ZA4D family 1 0
Platelet-activating factor receptor ligand 8-bromo-2-[4-(2-met... 2 2
Cell division cycle 7-related protein kinase inhibitor pyrrolo... 4 10
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 15 7
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 2 0
Coagulation factor X and Coagulation factor IX inhibitor 5-ami... 9 4
Ribosomal protein S6 kinase alpha-3 inhibitor N-(3-ethylimidaz... 2 2
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 3
Serine/threonine-protein kinase TBK1 and Inhibitor of nuclear ... 1 0
Serine/threonine-protein kinase Chk1 inhibitor SureCN5547496 f... 2 1
Glycogen synthase kinase-3 beta inhibitor GSK-3beta Inhibitor ... 1 0
Epidermal growth factor receptor ligand (E)-5-[4-(3-bromoanili... 11 0
Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... 12 7


External ID

Functional Category

Molecule Name

CFAMM00420911 CHEMBL2386272 Bioactive 3-(5-bromo-1-methylindol-3-yl)-4-imidazo[1,2-a]pyridin-3-ylpyrrole-2,5-dione

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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