CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13179
Family Name Nociceptin receptor and Mu-type opioid receptor ligand SureCN7586554 family
No. of Seeds 13 No. of Other Members 22
Family Centroid CFAMM00420948 Functional Category Bioactive
Superfamily Nociceptin receptor and Mu-type opioid receptor Binder Superfamily 9
Class Class 4128

Cousin Family NamesSeedsMembers
Substance-K receptor Ligand MEN-14933 Family 13 154
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Acetylcholinesterase Inhibitor 6-methyl-4-(4-phenylpiperazin-1... 6 622
Neuropeptide S receptor and Prelamin-A/C ligand CHEMBL1352632 ... 1 25
Acetylcholinesterase and Cholinesterase inhibitor [3-[4-(3,4-d... 3 18
Nociceptin receptor and Mu-type opioid receptor ligand N-ethyl... 8 3
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 2
D(4) dopamine receptor ligand 8-methoxy-3-[(4-nitrophenyl)meth... 1 1


External ID

Functional Category

Molecule Name

CFAMM00420948 CHEMBL238833 Bioactive SureCN7586554
CFAMM00420939 CHEMBL240074 Bioactive 1-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]-3-(methylsulfanylmethyl)benzimidazol-2-one
CFAMM00420938 CHEMBL391518 Bioactive 1-(2-hydroxyethyl)-3-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]benzimidazol-2-one
CFAMM00420922 CHEMBL239045 Bioactive 1-(ethoxymethyl)-3-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]benzimidazol-2-one
CFAMM00420952 CHEMBL241357 Bioactive 1-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]-3-(methylsulfonylmethyl)benzimidazol-2-one
CFAMM00420921 CHEMBL238795 Bioactive 1-[2-(dimethylamino)ethyl]-3-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]benzimidazol-2-one
CFAMM00420927 CHEMBL393960 Bioactive SureCN7584796
CFAMM00420935 CHEMBL391234 Bioactive methyl 3-[3-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]propanoate
CFAMM00420951 CHEMBL238637 Bioactive methyl 2-[3-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]acetate
CFAMM00420942 CHEMBL239260 Bioactive 1-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]-3-(2-oxobutyl)benzimidazol-2-one
CFAMM00420920 CHEMBL239043 Bioactive AGN-PC-076DAR
CFAMM00420926 CHEMBL401248 Bioactive SureCN7590210
CFAMM00420934 CHEMBL391422 Bioactive 1-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]-3-(methylsulfinylmethyl)benzimidazol-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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