CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13185
Family Name Beta-secretase 1 and Beta-secretase 2 inhibitor SureCN14726714 family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00420983 Functional Category Bioactive
Superfamily Beta-secretase 1 and Beta-secretase 2 Binder Superfamily 10
Class Class 3069

Cousin Family NamesSeedsMembers
secretase Inhibitor LY2886721 Family 1 2
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Metabotropic glutamate receptor 5 Ligand 3-cyano-n-(6-methylpy... 4 3
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Proto-oncogene tyrosine-protein kinase Src Inhibitor 5,7-diphe... 2 11
Metabotropic glutamate receptor 5 Ligand 3-cyano-5-fluoro-n-(p... 2 9
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 8 12
Mast/stem cell growth factor receptor Kit and Mitogen-activate... 4 2
Protein kinase C theta type inhibitor (2-aminopyridin-3-yl)-[6... 4 1
Substance-P receptor ligand Netupitant family 5 2
Aurora kinase A and Aurora kinase B inhibitor 4-fluoro-N-[4-[(... 6 1
Beta-secretase 1 and Potassium voltage-gated channel subfamily... 2 11
Beta-secretase 2 and Beta-secretase 1 inhibitor N-[3-[(1S,7S)-... 7 4
Beta-secretase 1 inhibitor N-[3-[(4R,5R,6S)-2-amino-5-fluoro-4... 4 11
Beta-secretase 1 and Beta-secretase 2 inhibitor N-[3-[(4S)-2-a... 6 4
Beta-secretase 2 and Beta-secretase 1 inhibitor N-[6-[(4R)-2-a... 1 1
Beta-secretase 1 and Beta-secretase 2 inhibitor SureCN4964150 ... 3 0
Beta-secretase 2 and Beta-secretase 1 inhibitor N-[3-[(4R)-2-a... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00420982 CHEMBL2386719 Bioactive N-[6-[(4R)-2-amino-5,5-difluoro-4-methyl-6H-1,3-oxazin-4-yl]-5-fluoropyridin-2-yl]-5-cyanopyridine-2-carboxamide
CFAMM00420984 CHEMBL2386721 Bioactive SureCN14726711
CFAMM00420983 CHEMBL2386720 Bioactive SureCN14726714

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26235 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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