CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13188
Family Name Dual specificity tyrosine-phosphorylation-regulated kinase 1A and Dual specificity tyrosine-phosphorylation-regulated kinase 1B inhibitor methyl 9-(1,3-benzodioxol-5-ylamino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00420995 Functional Category Bioactive
Superfamily Dual specificity tyrosine-phosphorylation-regulated kinase 1B and Dual specificity tyrosine-phosphorylation-regulated kinase 1A Binder Superfamily
Class Class 3404

Cousin Family NamesSeedsMembers
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
Epidermal growth factor receptor Ligand 4-(5-bromoindole-3-yl)... 6 15
Dual specificity mitogen-activated protein kinase kinase 1 inh... 10 54
Aurora kinase A and Aurora kinase B inhibitor AGN-PC-00EQPZ fa... 3 4
Aurora kinase A inhibitor AGN-PC-00BCUF family 16 43
Receptor-type tyrosine-protein kinase FLT3 ligand 2-(6,7-dimet... 3 2
Inositol monophosphatase 1 and Microtubule-associated protein ... 1 12
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor 2-(4-hydroxy... 2 15
Dual specificity tyrosine-phosphorylation-regulated kinase 1A ... 7 7
Dual specificity tyrosine-phosphorylation-regulated kinase 1A ... 4 0
Dual specificity tyrosine-phosphorylation-regulated kinase 1A ... 2 0
Deoxycytidine kinase inhibitor 2-[5-[4-[(4,6-diaminopyrimidin-... 14 11
Epidermal growth factor receptor and Receptor tyrosine-protein... 3 7
Glucokinase inhibitor AGN-PC-03ZE4O family 4 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00420994 CHEMBL2386743 Bioactive methyl 9-(2,4-dimethoxyanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate
CFAMM00420992 CHEMBL2386745 Bioactive methyl 9-(4-fluoro-2-methoxyanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate
CFAMM00420996 CHEMBL2386754 Bioactive ethyl 9-(1,3-benzodioxol-5-ylamino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate
CFAMM00420995 CHEMBL2386753 Bioactive methyl 9-(1,3-benzodioxol-5-ylamino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27526 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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