CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13189
Family Name Dual specificity tyrosine-phosphorylation-regulated kinase 1A and Dual specificity tyrosine-phosphorylation-regulated kinase 1B inhibitor methyl 9-(4-fluoroanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate family
No. of Seeds 7 No. of Other Members 7
Family Centroid CFAMM00421008 Functional Category Bioactive
Superfamily Dual specificity tyrosine-phosphorylation-regulated kinase 1B and Dual specificity tyrosine-phosphorylation-regulated kinase 1A Binder Superfamily
Class Class 3404

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase C Inhibitor SNS-314 Family 2 75
Aurora kinase B and Aurora kinase A Inhibitor CYC116 Family 16 135
Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibi... 6 64
C-C chemokine receptor type 4 Ligand N-(4-tert-butylthiazol-2-... 3 9
Glycogen synthase kinase-3 beta and Mitogen-activated protein ... 4 23
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(4-acet... 4 12
Vascular endothelial growth factor receptor 2 and Mast/stem ce... 10 27
Inositol monophosphatase 1 and Microtubule-associated protein ... 1 12
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 5 27
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 2 18
TGF-beta receptor type-1 ligand 6-[(5E)-5-(4-methyl-3H-1,3-thi... 22 9
G1/S-specific cyclin-E1 and G1/S-specific cyclin-E2 inhibitor ... 5 1
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(1,4-di... 3 3
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor 2-(4-hydroxy... 2 15
Dual specificity tyrosine-phosphorylation-regulated kinase 1A ... 4 2
Dual specificity tyrosine-phosphorylation-regulated kinase 1A ... 4 0
Dual specificity tyrosine-phosphorylation-regulated kinase 1A ... 2 0
Epidermal growth factor receptor and Vascular endothelial grow... 7 0
Transient receptor potential cation channel subfamily V member... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00421002 CHEMBL2386744 Bioactive methyl 9-(4-bromo-2-fluoroanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate
CFAMM00421008 CHEMBL2386765 Bioactive methyl 9-(4-fluoroanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate
CFAMM00421001 CHEMBL2386770 Bioactive methyl 9-(2-bromo-4-fluoroanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate
CFAMM00421007 CHEMBL2386764 Bioactive methyl 9-(4-methylanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate
CFAMM00421006 CHEMBL2386766 Bioactive methyl 9-(4-cyanoanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate
CFAMM00421010 CHEMBL2386763 Bioactive methyl 9-anilino-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate
CFAMM00421009 CHEMBL2386748 Bioactive methyl 9-(2,4-difluoroanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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