CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13193
Family Name Metabotropic glutamate receptor 5 ligand AGN-PC-0DB8TJ family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00421016 Functional Category Bioactive
Superfamily Potassium voltage-gated channel subfamily H member 2 and Alpha-1A adrenergic receptor Binder Superfamily
Class Class 1163

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase PLK1 Inhibitor Bi 6727 Family 15 81
Smoothened homolog Inhibitor LDE225 Family 3 76
MK-6096 family 3 69
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
Peptidyl-prolyl cis-trans isomerase A Inhibitor 3-[3-(3-benzyl... 3 34
C-X-C chemokine receptor type 3 Ligand AMG-487 Family 28 73
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 2 3
Metabotropic glutamate receptor 5 Ligand 3-methoxy-n-(6-methyl... 3 15
Hepatocyte growth factor receptor ligand SureCN4492034 family 2 2
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 1 0
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 8
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 6
Tyrosine-protein kinase ABL1 and Breakpoint cluster region pro... 8 5
Orexin receptor type 1 and Orexin receptor type 2 ligand (1R,2... 6 1
Metabotropic glutamate receptor 5 and Cytochrome P450 3A4 liga... 3 7
Angiopoietin-1 receptor and Vascular endothelial growth factor... 5 0
Cathepsin S and Cathepsin K inhibitor AGN-PC-078ZDC family 4 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00421017 CHEMBL2386850 Bioactive AGN-PC-0DASD2
CFAMM00421016 CHEMBL2386849 Bioactive AGN-PC-0DB8TJ

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27075 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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