CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13199
Family Name Non-receptor tyrosine-protein kinase TYK2 ligand AGN-PC-0D0Z0U family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00421044 Functional Category Bioactive
Superfamily Non-receptor tyrosine-protein kinase TYK2 Binder Superfamily
Class Class 898

Cousin Family NamesSeedsMembers
Smoothened homolog Inhibitor LDE225 Family 3 76
Proto-oncogene tyrosine-protein kinase Src Inhibitor PD166285 ... 6 70
Bacterial outer membrane Inhibitor HKI-9924129 Family 19 85
Potassium voltage-gated channel subfamily H member 2 Ligand Be... 22 56
Bifunctional epoxide hydrolase 2 Inhibitor 6-amino-n-(2,4-dich... 10 116
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 2 3
Metabotropic glutamate receptor 5 Ligand 3-methoxy-n-(6-methyl... 3 15
Metabotropic glutamate receptor 5 ligand AGN-PC-09QLD2 family 1 2
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 2 0
Collagenase 3 inhibitor 4-[4-[[5-(2-ethoxyethyl)-2,4,6-trioxo-... 3 0
Non-receptor tyrosine-protein kinase TYK2 ligand AGN-PC-0D0YSZ... 10 0
Non-receptor tyrosine-protein kinase TYK2 ligand SureCN1298914... 3 0
Non-receptor tyrosine-protein kinase TYK2 ligand SureCN3514789... 1 0
Aurora kinase A and Aurora kinase B inhibitor AGN-PC-071H3F fa... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00421045 CHEMBL2387113 Bioactive AGN-PC-0D0YQE
CFAMM00421044 CHEMBL2387112 Bioactive AGN-PC-0D0Z0U

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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